The Current Status and Prospects of Poly(Lactic Acid) Applications in Clinical Treatment

Zhenqi Yang, Chang Qiao, Jiayun Liu,Tao Qin, Peng Gao,Jian Chen,Guoyong Yin

Journal of Biomedical Nanotechnology(2024)

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摘要
Poly(lactic acid) (PLA) is a biodegradable and bio-based polymer that has gained significant attention as an environmentally friendly alternative to traditional petroleum-based plastics. PLA is derived from renewable resources like corn starch or sugarcane through a fermentation process that converts sugars into lactic acid, which is then synthesized into lactic acid. As a bioabsorbable synthetic polyester, PLA has the following benefits, biodegradability, biodegradability, renewable source, non-toxic, reduced greenhouse gas emissions, energy savings. With the emergence of new manufacturing technologies, especially nanomaterial technology, PLA can be endowed with more structural and biological properties. This review discusses the current application of the PLA-based biomaterials in drug delivery systems, medical fixation devices, tissue regenerative engineering scaffolds and Provides viewpoints regarding their prospective utilization.
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