Solvent-involved synthesis of pyrrolidin-5-one-2-carboxamides via a sequential Ugi/olefination reaction

Na Chen, Tianyu Long,Han-Han Kong,Zheng-Wei Wu, Qing-Qing Yang,Nianyu Huang,Long Wang

Organic Chemistry Frontiers（2024）

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摘要

An unprecedented multi-component reaction with solvent participation and a novel conversion of sulfur ylides was developed via a Ugi/olefination reaction to construct pyrrolidin-5-one-2-carboxamides.

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