SETDB1 as a cancer target: Challenges and perspectives in drug design

Haifa Hassanie, André Berndt Penteado,Larissa Costa de Almeida, Raisa Calil,Flavio da Silva Emery,Leticia Veras Costa-Lotufo, Gustavo Trossini

RSC Medicinal Chemistry（2024）

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Genome stability is governed by chromatin structural dynamics, which modify DNA accessibility under the influence of intra- and inter-nucleosomal contacts, histone post-translational modifications (PTMs) and variations, besides the activity of...

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