Performance Assessment of Dielectrically Modulated Junctionless Rectangular Gate All Around FET Biosensor for Label Free Detection of Neutral Biomolecules

In this work, a Dielectrically Modulated Junctionless Rectangular Gate All Around Field Effect Transistor (DM-JLRGAA-FET) is demonstrated and explored for label free detection of neutral biomolecules. In comparison to its conventional architectures, proposed biosensor exhibits a significantly improved sensing and conjugation performance due to its remarkable structure, which enhances its performance by providing substantial rejection to SCEs (short channel effects) and strengthened gate control over channel electrostatics. Drain current sensitivity, surface potential, transconductance and output conductance are employed to determine the sensing competence of the proposed biosensor. The proposed biosensor offers maximum drain current sensitivity of 8.09 for keratin biomolecule. The detection will become quite difficult during conjugation of two or more biomolecules. The conjugation analysis is also investigated by effective dielectric constant approach governed by Bruggeman’s Model. The conjugations of Streptavidin-Keratin and Streptavidin-Zein is studied for various concentration in the cavity. Conjugations of Streptavidin and Keratin shows the highest sensitivity of 18.5