Novel Metamaterial Inspired SSP-WGM Resonator Based Highly Sensitive EM Biosensor for Noninvasive Measurement of Blood Glucose Using Aqueous Glucose Solution and Saliva

This paper introduces a novel spoof surface plasmon polariton (SSPP) based metamaterial-inspired electromagnetic (EM) biosensor for non-invasive diabetes analysis. The sensor design incorporates a spoof surface whispering gallery mode (SS-WGM) resonator, which effectively localizes the electric field within a specific region due to its slow-wave propagation. To achieve optimal sensitivity, a PDMS microfluidic channel is utilized to hold the sample (SUT) precisely on the region of maximum EM field concentration. Two different non-invasive samples, aqua solution mimicking blood, and human saliva, are used for evaluation. The comprehensive analysis reveals that this proposed microwave sensor holds great potential in advancing the development of modern lab-on-chip systems based on microwave technology.