Green Synthesis of Silver Nanoparticles Using Extracts of Cocculus Pendulus: Morphology and Antibacterial Efficacy Against Common Nosocomial Pathogens

The use of plant extract to synthesize nanoparticles has transformed the area of nanotechnology. Silver nanoparticles (AgNPs) were generated in this work using the leaves of Cocculus pendulus as a reducing and stabilizing agent. The extract of C. pendulus was analyzed using a gas chromatography-mass spectrometer. UV-visible spectroscopy (UV-visible), Fourier Transform Infrared, Zeta potential, and Transmission Electron Microscopy were used to analyze the bio-fabricated AgNPs. In addition, we describe the antibacterial and antioxidant characteristics of AgNPs produced. Analyses were used to describe the morphology of produced AgNPs, which had a typical size of 45 nm. AgNP was discovered to be extremely poisonous to gram-positive bacteria and was a promising antibiotic against bacterial infections. Furthermore, antioxidant assays revealed the greatest free radical scavenging activity. Finally, our findings show that C. pendulus can be used as a source for green synthesis of AgNPs with strong antioxidant and antibacterial properties in vitro.