PD-1-PD-L1 immunomodulatory pathway regulates cardiac regeneration
NATURE CARDIOVASCULAR RESEARCH(2024)
摘要
Adult hearts have inherently limited regenerative capabilities, such that injury results in lasting damage. The situation is different in neonatal mouse hearts, however, where a new study reveals a role for the immunomodulatory PD-1-PD-L1 pathway in regulating regeneration after injury.
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