PD-1-PD-L1 immunomodulatory pathway regulates cardiac regeneration

NATURE CARDIOVASCULAR RESEARCH(2024)

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摘要
Adult hearts have inherently limited regenerative capabilities, such that injury results in lasting damage. The situation is different in neonatal mouse hearts, however, where a new study reveals a role for the immunomodulatory PD-1-PD-L1 pathway in regulating regeneration after injury.
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