Self-sustaining inflammatory cycle causes memory impairment in neuropsychiatric lupus

Autoantibodies that develop in systemic lupus erythematosus (SLE) can cause long-term cognitive impairment that remains even after the systemic disease becomes quiescent. This study attributes the persistent cognitive symptoms of SLE to a self-sustaining neuroinflammatory process that continues indefinitely unless disrupted - which can be done using medications approved by the US Food and Drug Administration.