Currephila A, a New Chromanol Derivative from the Endophytic Fungus Curreya pityophila

A previously undescribed chromanol derivative, named currephila A (1), was isolated from the endophytic fungus Curreya pityophila, along with two known compounds (2 and 3). Their structures were elucidated based on spectroscopic methods, electronic circular dichroism, and spin-spin coupling constants. The cytotoxic activities of compounds 1 and 2 against human breast adenocarcinoma MCF-7 cells were evaluated.