Supplementary Table S3 from XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies

Supplementary Table S3: IFN-y production EC50 in mouse, human, and cynomolgus primary cells The ability of mXTX301 to induce IFN- production in mouse splenocytes and XTX301 to induce IFN- production in human and cynomolgus monkey PBMCs was assessed via ELISA. The EC50 was calculated as described in the statistical analysis section.