A bioetching-induced visualized-organic photoelectrochemical transistor dual-signal mode sensor for alkaline phosphatase detection

Cunhao Fan, Jingjie Lai,Xilong Zhou, Yuanhao Liu, Zhiying Shao, Kezuo Di,Fuheng You, Lijun Ding,Kun Wang

CHEMICAL COMMUNICATIONS(2024)

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摘要
A study of an integrated OPECT biosensor gate and the EC color-changing region on the same chip was carried out, achieving sensitive detection through bioetching-induced signal changes. Enzymatic bioetching enables specific alkaline phosphatase (ALP) detection by catalyzing the production of CdS, which modulates the channel current and generates a visual signal. Building and functioning of a visualized-OPECT sensor, along with real photographs of the sensing elements in action.
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