Durable complete response to PET-CT driven stereotactic radiation therapy plus pembrolizumab for pleomorphic Pancoast cancer: Case report and literature review

Alessandra Castelluccia,Angela Sardaro,Artor Niccoli Asabella,Antonio Rosario Pisani,Dino Rubini,Maurizio Portaluri,Francesco Tramacere

CLINICAL CASE REPORTS（2024）

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摘要

PET-driven SBRT plus pembrolizumab as first-line therapy against pleomorphic Pancoast cancer appears beneficial, probably due to high equivalent doses of SBRT on photopenic necrotic core and synergic immune system stimulation of immunoradiotherapy.

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关键词

image-guided radiation therapy,immune checkpoint inhibitors,Pancoast tumor,pleomorphic lung cancer,radioimmunotherapy,stereotactic body radiotherapy

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