Mobilization and Collection of HSCs in Children

AbstractPediatric hematopoietic stem cell (HSC) products are crucial components of hematopoietic cell transplantation (HCT) in children. This chapter provides an overview of the techniques and considerations involved in pediatric bone marrow (BM) collection and in stem cell apheresis. It covers patient selection, pre-procedure preparation, apheresis procedures, and post-procedure care. Additionally, specific considerations related to pediatric patients, such as ethical considerations, vascular access, and volume management, are discussed. This chapter will focus on the technical, physiological, and ethical problems in the field of HSC collection from children to ensure safe and efficient procedures.