Copper-Mediated Decarboxylative Amidination: Synthesis of O-Methyl-N-Alkylnitroisoureas

ADVANCED SYNTHESIS & CATALYSIS(2024)

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摘要
Copper-catalyzed decarboxylation of peroxides in the presence of O-methyl-N-nitroisourea provides an access to O-methyl-N-alkylnitroisoureas, an underdeveloped class of nitrogenated compounds, which can be regarded as isocyanate surrogates and find useful as AB-type monomers, for polyurethane synthesis.
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关键词
N-alkylnitroisourea,amidination,peroxide,copper catalysis,urea,radical decarboxylation
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