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Asymmetric Synthesis of Unnatural Α-Amino Acids Through Photoredox-Mediated C–O Bond Activation of Aliphatic Alcohols

Chemical science(2024)

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摘要
A practical protocol for the stereoselective synthesis of unnatural α-amino acids is disclosed, using ubiquitous aliphatic alcohols as radical precursors to form the α-amino acid backbone under redox-neutral photoredox-mediated conditions.
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