Reporting of interventional clinical trial results in an academic center: a survey of completed studies

Anne Sophie Alix-Doucet, Constant Vinatier, Loïc Fin,Hervé Léna, Hélène Rangé, Clara Locher,Florian Naudet

BMC Medical Research Methodology(2024)

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摘要
The dissemination of clinical trial results is an important scientific and ethical endeavour. This survey of completed interventional studies in a French academic center describes their reporting status. We explored all interventional studies sponsored by Rennes University Hospital identified on the French Open Science Monitor which tracks trials registered on EUCTR or clinicaltrials.gov, and provides an automatic assessment of the reporting of results. For each study, we ascertained the actual reporting of results using systematic searches on the hospital internal database, bibliographic databases (Google Scholar, PubMed), and by contacting all principal investigators (PIs). We describe several features (including total budget and numbers of trial participants) of the studies that did not report any results. The French Open Science Monitor identified 93 interventional studies, among which 10 (11 https://osf.io/q5hcs
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关键词
Open Science,Clinical studies,Results,Publication,Audit
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