Effects of standardized aronia melanocarpa extract on cardiovascular system: from basic to applied investigation

This study summarizes the effects standardized Aronia melanocarpa extract (SAE) on different pathophysiological processes linked with cardiovascular system from both animal and human investigations. In basic researches we estimated the influence of SAE on rats with metabolic syndrome (MetS) and polycystic ovary syndrome (PCOS). Human studies aimed to assess the impact of SAE in patients with MetS and in professional handball players. SAE had the ability to lower blood pressure and exert benefits on in vivo and ex vivo heart function. Furthermore, SAE induced a wide range of beneficial effects in human researches. Overall, SAE could be a promising strategy to reduce cardiovascular risk.