Growth in children with nephrotic syndrome: a post hoc analysis of the NEPTUNE study

Aesha Maniar,Debbie S. Gipson,Tammy Brady,Tarak Srivastava,David T. Selewski,Larry A. Greenbaum,Katherine M. Dell,Frederick Kaskel,Susan Massengill,Cheryl Tran,Howard Trachtman,Richard Lafayette,Salem Almaani,Sangeeta Hingorani,Chia-shi Wang,Kimberly Reidy,Gabriel Cara-Fuentes,Rasheed Gbadegesin, Kevin Myers,Christine B. Sethna

Pediatric Nephrology（2024）

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摘要

Steroids, the mainstay of treatment for nephrotic syndrome in children, have multiple adverse effects including growth suppression. Anthropometric measurements in children < 18 years enrolled in the Nephrotic Syndrome Study Network (NEPTUNE) were collected. The longitudinal association of medication exposure and nephrotic syndrome characteristics with height z-score and growth velocity was determined using adjusted Generalized Estimating Equation regression and linear regression. A total of 318 children (57.2

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关键词

Body mass index (BMI),Height,Nephrotic syndrome,Steroids,Weight

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