Characterization of NMCR-3, NMCR-4 and NMCR-5, three novel non-mobile colistin resistance determinants: implications for MCR-3, MCR-7 and MCR-5 progenitors, respectively

Yating Guo,Geng Zou,Anusak Kerdsin,Constance Schultsz, Can Hu, Weicheng Bei,Huanchun Chen,Jinquan Li,Yang Zhou

Drug Resistance Updates（2024）

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摘要

In this study, the progenitors of MCR-3, MCR-7 and MCR-5, namely NMCR-3, NMCR-4 and NMCR-5, were firstly discovered and indicating Aeromonas was a natural reservoir for MCR-3 and MCR-7. Furthermore, different evolutionary models for MCR-3, MCR-7 and MCR-5 were proposed.

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关键词

Colistin,MCR,NMCR,Aeromonas

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