Isavuconazole for the Treatment of Fungal Infections: a Real-Life Experience from the Fungal Infection Network of Switzerland (FUNGINOS)

This analysis of 116 isavuconazole therapy courses shows that hepatic test disturbances (HTDs) were relatively frequent (29% of cases) but rarely led to treatment interruption (5%). Importantly, patients with baseline HTDs, including those attributed to a first-line triazole, did not exhibit a higher risk of subsequent HTD under isavuconazole therapy.