60. Meta-Analysis of Functional Magnetic Resonance Imaging Studies Reveals Abnormal Patterns of Neural Activation in Panic Disorder and Agoraphobia

Panic disorder (PD) and agoraphobia (AG) are prevalent and comorbid anxiety disorders. Studies using functional magnetic resonance imaging (fMRI) have identified different patterns of activation in PD/AG patients and healthy controls. However, these studies have often lacked sufficient statistical power and reported inconsistent results. This meta-analysis seeks to advance our understanding of the neural basis of PD and AG by identifying patterns of neural activation across task-based fMRI activation studies of individuals with PD/AG compared to healthy controls.