Virological Traits of the SARS-CoV-2 BA.2.87.1 Lineage.

Vaccines(2024)

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摘要
Transmissibility and immune evasion of the recently emerged, highly mutated SARS-CoV-2 BA.2.87.1 are unknown. Here, we report that BA.2.87.1 efficiently enters human cells but is more sensitive to antibody-mediated neutralization than the currently dominating JN.1 variant. Acquisition of adaptive mutations might thus be needed for efficient spread in the population.
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关键词
SARS-CoV-2,BA.2.87.1,spike protein,host cell entry,ACE2 binding,antibody evasion
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