Aggregation-induced emission photosensitizer for antibacterial therapy of methicillin-resistant Staphylococcus aureus.
Chemical communications (Cambridge, England)(2024)
摘要
A cationic aggregation-induced emission photosensitizer (AIE-PS) MNNPyBB has been reported to have antibacterial effects against both Gram-positive and Gram-negative bacteria. The bacterial kill mechanism has been investigated and elucidated. In a methicillin-resistant Staphylococcus aureus subcutaneous infection model, wound closure has been achieved with normal re-epithelialization and preserved skin morphology.
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