A proposed simplified definition of metabolic syndrome in children and adolescents: a global perspective

Xin’nan Zong,Roya Kelishadi,Hae Soon Kim,Peter Schwandt, Tandi E. Matsha,Jose G. Mill,Carmelo Antonio Caserta,Carla Campos Muniz Medeiros,Anastasios Kollias,Peter H. Whincup,Lucia Pacifico,Abel López-Bermejo,Min Zhao,Miaobing Zheng,Bo Xi

BMC Medicine（2024）

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摘要

Metabolic syndrome (MetS) is becoming prevalent in the pediatric population. The existing pediatric MetS definitions (e.g., the International Diabetes Federation (IDF) definition and the modified National Cholesterol Education Program (NCEP) definition) involve complex cut-offs, precluding fast risk assessment in clinical practice. We proposed a simplified definition for assessing MetS risk in youths aged 6–17 years, and compared its performance with two existing widely used pediatric definitions (the IDF definition, and the NCEP definition) in 10 pediatric populations from 9 countries globally (n = 19,426) using the receiver operating characteristic (ROC) curve analyses. In general, the total MetS prevalence of 6.2

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关键词

Metabolic syndrome,Central obesity,Hypertension,Cardiovascular risk factors,Child,Waist-to-height ratio,Adolescent

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