Urinary incontinence after radical prostatectomy for prostate cancer-data from 17,149 patients from 125 certified centers

Background: In addition to erectile dysfunction, urinary incontinence is the most common functional limitation after radical prostatectomy (RPE) for prostate cancer (PCa). The German S3 guideline recommends informing patients about possible effects of the therapy options, including incontinence. However, only little data on continence fromroutine care in German-speaking countries after RPE are currently available, which makes it difficult to inform patients. Objective: The aim of this work is to present data on the frequency and severity of urinary incontinence after RPE from routine care. Materials and methods: Information from the PCO (Prostate Cancer Outcomes) study is used, which was collected between 2016 and 2022 in 125 German Cancer Society (DKG)-certified prostate cancer centers in 17,149 patients using the Expanded Prostate Cancer Index Composite Short Form (EPIC-26). Changes in the "incontinence" score before (T0) and 12 months after RPE (T1) and the proportion of patients who used pads, stratified by age and risk group, are reported. Results: The average score for urinary incontinence (value range: 0-worst possible to 100-best possible) was 93 points at T0 and 73 points 12 months later. At T0, 97% of the patients did not use a pad, compared to 56% at T1. 43% of the patients who did not use a pad before surgery used at least one pad a day 12 months later, while 13% use two ormore. The proportion of patients using pads differs by age and risk classification. Conclusion: The results provide a comprehensive insight into functional outcome 12 months after RPE and can be taken into account when informing patients.