Notes from the Field: Potential Outbreak of Extrapulmonary Mycobacterium abscessus subspecies massiliense Infections from Stem Cell Treatment Clinics in Mexico - Arizona and Colorado, 2022.

Minh-Vu H Nguyen,Nabeeh A Hasan,Vinicius Calado Nogueira De Moura,L Elaine Epperson, Christopher A Czaja,Helen Johnston, Nicholas Laramee, Kelsey Orten, JulieAnna Rivas, Siru Prasai, Marissa K Grossman,Kiran M Perkins,David E Griffith,Reeti Khare,Michael Strong,Charles L Daley

MMWR. Morbidity and mortality weekly report(2024)

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摘要
Mycobacterium abscessus is an intrinsically drug-resistant, rapidly growing, nontuberculous mycobacterium; extrapulmonary infections have been reported in association with medical tourism (1). During November-December 2022, two Colorado hospitals (hospitals A and B) treated patient A, a Colorado woman aged 30-39 years, for M. abscessus meningitis. In October 2022, she had received intrathecal donor embryonic stem cell injections in Baja California, Mexico to treat multiple sclerosis and subsequently experienced headaches and fevers, consistent with meningitis. Her cerebrospinal fluid revealed neutrophilic pleocytosis and grew M. abscessus in culture at hospital A. Hospital A's physicians consulted hospital B's infectious diseases (ID) physicians to co-manage this patient (2).
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