Development of 3D scaffolds models using parameterized modeling

Abstract Tissue engineering is a technique for regenerating living tissue using portions of the patient's own tissue, which are dissociated into cells and cultured on biological or synthetic supports before being transferred to the patient. In this context, the present work seeks to develop implant models (scaffolds) for the replacement of trabecular bone tissue, in accordance with requirements like porosity and interconnected pores. All design development was aimed at the manufacturing of scaffolds using material extrusion process. For the development of this work, the Grasshopper program was utilized, an extension of Rhino that facilitates the creation of structures easily modifiable by parameters. The model developed involves applying the Voronoi 2D diagram in two perpendicular planes to generate extruded structures along a vector perpendicular to the plane of the respective diagram. This approach aims to create a pore structure interconnected in two directions. Prototypes have been produced that fulfill most of the properties required by a scaffold. In addition, the geometry of the prototypes was very close to the original model, even using low resolution 3D printers.