Copper Catalyzed Chemoselective Nitro Reduction
Synthesis(2024)
摘要
The reduction of nitro compounds into the highly valuable anilines was reported using a Cu-catalyst and B2Pin2. The reaction proceeded under very mild reaction conditions and showcased an excellent functional group tolerance. This method was applied to a large panel of nitro derivatives including biorelevant molecules and important synthetic intermediates toward the synthesis of API. This novel reaction manifold intends to provide a complementary approach to the existing portfolio of nitro-reduction methods.
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