An “out of the Box” Approach for Prevention of Ketoacidosis in Youth with Poorly Controlled Type 1 Diabetes: Combined Use of Insulin Pump and Long-Acting Insulin

Poorly controlled adolescents living with type 1 diabetes (T1D) and pump failure of insulin delivery leading to diabetic ketoacidosis (DKA) are still challenging in the western world. To investigate the effect of a combination modality of long-acting insulin for basal coverage and a pump for boluses, on the incidence of DKA and glycemic parameters in pediatric and young adults with poorly controlled T1D. This multicenter, observational retrospective study included 55 patients (age range 3–25 years, 52.7