University of Medicine and Pharmacy at Ho Chi Minh City is one of the most highly ranked universities of medicine and pharmacy in Vietnam. It offers graduate and postgraduate education in medicine, pharmacy.
To determine the impact of low versus atmospheric oxygen tension during only the pre-maturation phase of biphasic capacitation in vitro maturation. The study involved sibling oocytes (532 cumulus-oocyte complexes [COCs] from 20 participants [mean age 29.5 ± 2.5 years]) with polycystic ovary syndrome undergoing CAPA-IVM without gonadotrophins. After oocyte pick-up (OPU), COCs were randomized to undergo pre-maturation under low or atmospheric oxygen, then IVM culture at 20
Neptunia oleracea Lour., commonly known as “Yellow Pan Weed, Water Mimosa or Water Sensitive Plant”, is a wild aquatic plant of the genus Neptunia in the family Fabaceae, and its parts can be used as food and in medicine. With further exploration, its applications are found in various fields, including food, agriculture, and medicinal herbs. This review summarizes traditional knowledge by integrating it with scientific evidence related to N. oleracea’s phytochemical compounds, pharmacological activities, and therapeutic potential. This narrative review analyzed 50 documents from databases, including Web of Science, Scopus, Google Scholar, ScienceDirect, SpringerLink, PubMed, and other online databases (1790–2025), focusing on articles and textbooks on N. oleracea’s botany, nutritional benefits, traditional uses, phytochemistry, and pharmacological properties. 54 metabolites, including pheophorbides, phenolics, flavonoids, and other compounds, were found in N. oleracea. The extracts from N. oleracea parts and its isolated compounds have been shown to possess various biological properties, including antioxidant, antimicrobial, anti‐inflammatory, analgesic, anticancer, antiulcer, astringent, anti-5α-reductase, and anti-diabetic activities. These pharmacological properties are closely associated with the presence of phenolic compounds, particularly flavonoids. Various parts of N. oleracea contain nutritional components, minerals, and vitamins. Although some evidence supports the link between traditional uses and modern pharmacology, significant knowledge gaps still hinder its integration into evidence-based clinical applications. In the future, prioritizing large-scale clinical studies and developing combination formulations will further elucidate and expand the therapeutic potential of N. oleracea.
To determine the incidence and identify independent risk factors of central venous catheter (CVC)-related thrombosis in critically ill children admitted to a pediatric intensive care unit in a middle-income country, and to contribute context-specific prospective data relevant to clinical practice. In this prospective observational study, catheterization episodes in children undergoing central venous catheter (CVC) placement were systematically screened with Doppler ultrasonography within 24–48h after insertion and weekly thereafter. Clinical and catheter-related variables were analyzed using multivariable generalized estimating equation models with a logit link to identify independent predictors of catheter-associated thrombosis. A total of 129 catheters, including 105 infusion catheters and 24 hemodialysis catheters, corresponding to 111 catheterization episodes were evaluated in 103 children. Thrombotic events related to CVCs occurred in 22 of 111 catheterization episodes (19.8
Obstructive sleep apnea (OSA) is associated with decreased daytime functional outcomes and increased psychological stress. However, the specific profile of this burden, particularly in the Vietnamese population, remains understudied. This study aimed to analyze sleep-related functional outcomes and psychological stress in a population of untreated Vietnamese patients with OSA. We conducted a cross-sectional study of 61 untreated patients with OSA (78.7
Stroke is a leading cause of long-term disability and is often accompanied by psychological difficulties that may affect recovery and social reintegration. To estimate the rates of anxiety and depression, the prevalence of anxiety and depression among stroke survivors and to examine their associations with social support and functional independence. A cross-sectional study included 157 post-stroke patients. Anxiety and depression were assessed using Hospital Anxiety and Depression Scale, social support using Medical Outcomes Study Social Support Survey, and functional status using the Barthel Index. Associations were examined using both univariable and multivariable logistic regression analyses. Among the participants, 14.0
