The Libyan International Medical University (Arabic: الجامعة الليبية الدولية للعلوم الطبية) is a private university established in Benghazi, Libya, with the purpose of teaching medicine. It is the first private medical university in Libya.Its doors were opened to enrolled students on October 15, 2007. According to university references, over 200 students had enrolled under its faculties:One of the university's major points is its focus on international partnerships and meeting the level of other international medical teaching institutes. The teaching policy emulates those of many established universities and is mainly problem-based learning.The National Quality Assurance committee of Libya visited all the universities to evaluate them on two bases: facilities and program. The Libyan International Medical University attained a very advanced position in this evaluation in both aspects.The Libyan Ministry of Health granted LIMU students the privilege of training at the national health care centers and hospitals..
BACKGROUND:Urolithiasis is a prevalent urological condition, and Non-Contrast Computed Tomography (NCCT) is the gold standard for diagnosis. In recent years, there has been growing interest in investigating machine learning (ML)- based detection of urolithiasis and the wider potential of AI in urology. PURPOSE:To synthesise the diagnostic accuracy of ML-based UTS detection on NCCT and in externally validated cohorts. MATERIALS AND METHODS:We performed a systematic review and bivariate meta-analysis of studies evaluating ML for detecting urinary stones. We used QUADAS-2 to assess the risk of bias. Subgroup analyses examined performance by model type, classification task, stone site, dataset source, and CT orientation. Bivariate meta-regression was performed to further explore heterogeneity. Publication bias was assessed using Deeks' test. The study was prospectively registered in Prospero (CRD42024542409). RESULTS:Forty-five studies were included qualitatively. 24 studies (49,277 test images) provided extractable 2 × 2 data for meta-analysis. For NCCT (10 studies), pooled sensitivity was 96% (95% CI 92-98%) and pooled specificity was 98% (95% CI 97-99%). In externally validated NCCT cohorts (4 studies; 1,056 images), pooled sensitivity was 95% (95% CI 92-97%) and pooled specificity was 96% (95% CI 70-100%). Subgroup performance remained high, but heterogeneity persisted; meta-regression found stone site contributed to variability (p = 0.014), while other moderators were not significant. Deeks' test showed no small-study effects (p = 0.571). CONCLUSION:ML models show high image-level diagnostic performance for stone detection on NCCT and may support radiologists as decision support tools. Translation is limited by heterogeneity and limited external validation. Future studies should move beyond detection-alone tasks towards clinically meaningful outputs that are actionable for radiologists and downstream clinicians, including urologists and nephrologists.
Background: Phragmites australis, a grass species of the Poaceae family, has promising therapeutic potential in traditional medicine. Its phytochemical composition varies depending on its geographical origin, genetic differences, and extraction methods. Aim: This study assessed the phytochemical profile and biological activities of Phragmites australis aqueous extract (PAAE). Methods: The phenolic profile of the extract was determined using liquid chromatography/electrospray ionization mass spectrometry (LC-ESI-MS). The cytotoxic effects of PAAE on breast (MCF-7), hepatocellular (HepG2), and colon (Caco-2) cancer cell lines were evaluated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The antioxidant capacity was assessed by DPPH and FRAP assays. Furthermore, the antimicrobial activity was tested against four bacterial and two fungal species, and the antiviral activity was evaluated against HSV-1 and HAV. Results: The polyphenolic and flavonoid contents of the PAAE were 65.94 mg GAE/g and 22.7 mg AAE/g, respectively.LC‒MS analysis revealed high levels of various phenolic compounds, including rutin, quercetin, luteolin-7-O-glucoside, caffeic acid, apigenin-6-C-glucoside, protocatechuic acid, coumaric acid, and feruloyl-quinic acid derivatives.The MTT cell viability assay indicated concentration-dependent inhibition of cell lines, with IC₅₀ values of 20.67 ± 0.09 µg/mL for MCF-7 cells, 10.4 ± 0.08 µg/mL for Caco-2 cells, and 20.67 ± 0.09 µg/mL for HepG2 cells. Furthermore, PAAE exhibited significant antibacterial activity against Bacillus subtilis and Klebsiella pneumoniae, as well as significant antiviral activity, reducing HAV and HSV-1 replication by 99.45% and 79.76%, respectively, at nontoxic concentrations. Conclusion: This study is the first to investigate Phragmites australis from Benghazi, Libya, revealing its rich diversity of polyphenols and flavonoids, along with notable antioxidant, antibacterial, and antiviral activities.
Background: On the 11th of March 2020, the World Health Organization categorized COVID-19 as severe enough to warrant the act of social distancing. In response, the Libyan International University (LIU) implemented online learning platforms to reduce the rate of transmission among students and staff, allowing them to study and instruct from anywhere, at any time, and with more convenience. This study aimed to explore students’ attitudes and perceptions towards online learning in medical education. Methodology: A cross-sectional study involving 250 medical students was conducted. The completed questionnaire comprised questions related to demographic characteristics and their online learning experience. Statistical significance and inferential statistics were determined through SPSS software analysis.
Leptospirosis is a common zoonotic infection worldwide but remains rare in the Middle East, including the United Arab Emirates. We report a case of a 36-year-old male who presented with high-grade fever, severe myalgia, headache, vomiting, dark urine, and altered mental status following recent travel from an endemic area where he worked as a paddy field farmer. Clinical examination and laboratory findings revealed septic shock, acute kidney injury, marked hyperbilirubinemia, and severe thrombocytopenia, consistent with multi-organ dysfunction syndrome. Based on the clinical presentation and exposure history, leptospirosis was strongly suspected, and Leptospira IgM serology was sent. The patient was managed in the intensive care unit with supportive care and broad-spectrum antibiotics, leading to gradual clinical improvement. This case highlights the need to consider leptospirosis in acute febrile illness with jaundice and organ dysfunction, even in non-endemic regions.
Background: Poor glycemic control in children with type 1 diabetes leads to serious complications affecting growth, development, and quality of life. In Libya, data are limited. Our study assesses glycemic control and identifies risk factors associated with poor control, to guide better man agement and prevent long-term complications in young patients. Methodology: A cross-sectional study was conducted at Benghazi Chil dren’s Hospital, involving 120 children and adolescents aged (<18 years) with type 1 diabetes mellitus for over a year. Glycemic control was assessed using glycated haemoglobin and categorized as good (HbA1c <7.5%) or poor (HbA1c ≥7.5%). Logistic regression analysis was performed to identify significant risk factors associated with poor glycemic control. Results: The study found that 93.3% of participants had poor glycemic control, with a mean HbA1c of 10.2%. Adolescents and prolonged use of insulin pen needles for more than one day were identified as risk factors for poor glycemic outcomes, with p-values of 0.030 and 0.014, respec tively. Conclusion: Poor glycemic control was highly prevalent among children and adolescents with type 1 diabetes mellitus attending Benghazi Chil dren’s Hospital. Adolescence (11–18 years) and reuse of insulin pen nee dles were associated with poor glycemic control. These findings highlight the need for targeted interventions and strengthened diabetes manage ment strategies.
