The LMU Klinikum (until 2020 Klinikum der Universität München) is the merged hospital complex of the Ludwig Maximilian University of Munich (LMU), including the Campus Innenstadt in the city center and the Campus Großhadern in Hadern. The hospital houses more than 2000 beds with 48 clinics, institutes and departments, making it one of the largest hospitals in Europe. In 2015, the Ludwig Maximilian University was ranked the leading German university in the subject area "Clinical, pre-clinical and health" according to the Times Higher Education World University Ranking.
Acute flank pain due to ureteral calculi is a common presentation in emergency departments (EDs). Decisions between conservative management and inpatient intervention remain difficult in the absence of absolute indications. This study aims to identify size-stratified predictors to assist ED decision-making in ureterolithiasis. This was a single-center retrospective study of patients presenting in the ED of a tertiary center with acute renal colic between October 2020 and November 2024. A total of 752 patients with CT-confirmed ureteral stones were included and analyzed. Receiver operating characteristic (ROC) analysis identified a 5.65-mm threshold; operationalized as 6 mm in the subsequent analyses. After size-based stratification, uni- and multivariate regression analyses were conducted to identify predictors for inpatient admission in the <6 mm subgroup and predictors for discharge in the ≥6 mm subgroup, respectively. Overall, 77
OBJECTIVES:Resin infiltration is a micro-invasive treatment option to manage enamel opacities, arresting lesion progression and improving esthetics. As restorative interventions may be required during or after infiltration treatment, this study evaluated the bond strength of composite resin to infiltrated bovine enamel, focusing on the effect of enamel priming. METHODS:Bovine sound incisors (n = 120) were used and demineralized lesions were created in half of the specimens. Prior to resin infiltration (Icon, DMG, Hamburg, Germany), the etched enamel surface was dried with either Icon Dry or Icon Prime (DMG), the later containing 10-Methacryloyloxydecyl dihydrogen phosphate (10-MDP). A resin composite (Ecosite Elements, DMG) was placed without any adhesive and half of the specimens in each group underwent ageing using thermocycling (5°C/55°C, 5000 cycles); the other half served as non-aged controls. Notched-edge shear bond strength (SBS) was measured after storage of the specimens in water at 37°C for 24 h. A three-way ANOVA (α = 0.05) was used to analyze the effects of enamel priming (Icon Dry/Icon Prime), enamel type (sound/demineralized) and aging condition (aged/non-aged). Failure mode analysis was performed by SEM. RESULTS:Enamel priming with Icon Prime significantly increased SBS compared to Icon Dry (p = 0.012). No significant main effects were observed for enamel type (p = 0.671) or aging condition (p = 0.794). Adhesive failure predominated at the enamel-infiltrant interface; no interfacial degradation was observed after thermocycling in Icon Prime-pretreated specimens. SIGNIFICANCE:Bond strength between composite resin and infiltrated enamel can be clinically sufficient without an adhesive if the oxygen inhibition layer is preserved, enabling simplified workflows. Long-term bond durability depends on the aging resistance of the infiltrant layer itself, making enamel priming a key determinant.
This study aimed to assess whether children with anterior molar–incisor hypomineralisation (MIH) experience bullying related to dental appearance and to evaluate whether a minimally invasive resin infiltration treatment of MIH-affected anterior teeth could reduce self-reported bullying and improve Oral Health–Related Quality of Life (OHRQoL). Twenty-one children aged 8–14 years with MIH involving anterior teeth and self-reported bullying were enrolled in a single-arm clinical trial. Eligibility required affirmative responses to two items of the Child Perceptions Questionnaire (CPQ) specifically addressing bullying related to oral conditions, ensuring that all participants presented both anterior MIH and concomitant bullying experiences. Icon resin infiltrant (DMG, Germany) was applied to visible opacities. The CPQ was then administered at baseline and one month after treatment to assess changes in OHRQoL, whilst bullying experiences were reassessed at baseline and three months post-treatment. Data were analysed using Jamovi 2.3.28 with the McNemar test, Wilcoxon signed-rank test, Friedman test, and Durbin–Conover post hoc comparisons. All participants reported bullying at baseline, whereas none did so at the three-month follow-up (p < 0.001). Significant improvements were observed in the emotional and social domains of OHRQoL 1 month after treatment (p < 0.001), and these benefits were sustained over time. Minimally invasive resin infiltration of anterior MIH lesions effectively eliminated self-reported bullying and significantly improved OHRQoL, highlighting the clinical and psychosocial benefits of early aesthetic intervention in affected children.