NHS Tayside is an NHS board which forms one of the fourteen regions of NHS Scotland. It provides healthcare services in Angus, the City of Dundee and Perth and Kinross. NHS Tayside is headquartered at Ninewells Hospital in Dundee. It currently has one of the largest hospitals in the world and also one of the largest teaching hospitals in the world within its boundaries (Ninewells Hospital, Dundee).It has three Health and Social Care Partnerships (HSCPs): Angus, Dundee and Perth & Kinross.
BACKGROUND:Women are more likely to report suicidal ideation and make suicide attempts, while men are more likely to die by suicide. There has been much discussion of the possible contribution of masculinity (i.e., attitudes, beliefs, and behaviours understood to be 'masculine' through construction of gendered identities in local contexts) to this gender paradox of suicide. Here we report the first systematic literature review, meta-analysis, and meta-regression testing relationships between measures of masculinity and suicidality. METHODS:We searched for articles using the following search terms in Google Scholar, Web of Science, PubMed, and APA PsychINFO in July 2024 (("gender role*" OR "gender-role*" OR "sex role*" OR "sex-role*" OR "masculin*" (TOPIC)) AND ("suicid*" (TOPIC))). We excluded papers which examined non-suicidal self-injury, were not based on individual-level valid and reliable quantitative measures of masculinity and suicidality, and which did not provide sufficient statistical information to compute effect size. RESULTS:Across 23 studies the relationship between the multiple and diverse measures of masculinity and of suicidality overall was non-significant (r = 0·03 [95% CI: -0·01, 0·1], z = 1.75, p = 0.341) and showed significant heterogeneity. Given the range of operationalisations of masculinity included, and the high heterogeneity, we urge caution in interpreting the pooled overall relationship. Meta-regression showed moderation of the overall relationship by both measure of masculinity and suicidality. That is, the positive relationship between masculinity and suicidality was stronger for measures of masculinity that focussed on emotional restriction and pursuit of status, and for suicidal action than ideation. Conversely, there were inverse relationships between strength-based measures of masculinity and suicidality. LIMITATIONS:Our results demonstrated significant heterogeneity, and measures of masculinity are likely to be largely outdated. CONCLUSIONS:Our results suggest there is value in further work identifying specific aspects of contemporary psychological masculinity which link to suicidality, which is of relevance to clinical assessment and management of suicidality.
Scotland has comprehensive vision screening at age 3.5–5.5 years, with 85
Abstract Background and aims Overdose induced by illicit drug use is a significant public health threat in many settings globally. Many such overdoses occur in the context of lone use in private spaces, in the absence of potential first responders. Chest-worn biosensors have the potential to detect respiratory depression which signal overdose and alert first responders, enabling rapid reversal. However, the acceptability of this approach to people who use drugs and other key stakeholders are not known. We aimed to investigate these outcomes in this qualitative sub-study, which is part of a larger trial investigating this intervention. Methods Semi-structured interviews and focus groups were conducted with participants who completed the study protocol ( n = 20), partially completed the study protocol ( n = 1) and stakeholder groups ( n = 8) about device acceptability. Verbatim transcripts were analysed using reflexive thematic analysis. Factors influencing device acceptability for PWUD were interpreted using the concepts of the COM-B behaviour model. Discussions around implementation with stakeholder groups utilised Normalisation Process Theory to further appraise the intervention and its integration into existing services. Results Experiences with overdose or drug-related deaths (DRD) were identified within qualitative data as motivating factors for device wear. First responder groups stressed the importance of patient choice and device accuracy. The accelerometer sensor was found to be acceptable to people who use drugs (PWUD) and was utilised to monitor respiratory patterns. Stakeholders recognised the potential of these devices to play a part in the management of overdose and identified necessary requirements to ensure successful implementation of the device, such as funding allocation, potential barriers and integration into existing services. Conclusions The chest-worn biosensor was acceptable to PWUD, driven by personal experiences with overdose risks, and were viewed by stakeholders as a promising tool for overdose management. Successful implementation will require ensuring device accuracy, respecting patient choice, securing funding, and integrating the technology into existing services. Clinical trials registration Researchregistry7351
OBJECTIVE:Inherited Retinal Disorders (IRDs) are a leading cause of blindness in working age adults. With the emergence of therapeutic approaches and pre-implantation genetic testing, obtaining a molecular diagnosis is increasingly important. As such we aimed to determine the caseload of IRD patients presenting to Scottish ophthalmology services over a 5-year period, and evaluated the diagnostic approaches used and results of genetic testing in order to determine any established inherited cause. SUBJECTS:Data from all patients presenting to ophthalmology services across Scotland from January 2018 to January 2023 diagnosed with an IRD were collected. History and examination findings were recorded, as were the methods of genetic testing used, the identified genetic variants and the time taken for molecular reporting. RESULTS:532 patients were included in the analysis. The most common clinical diagnosis was retinitis pigmentosa (RP) (42.4%), followed by Stargardt Disease (9.0%), with Usher syndrome the most common syndromic RP. The most common initial test was a 176 gene panel, followed by direct testing for ABCA4, with different regions pursuing different testing strategies. 67.4% of patients received a molecular diagnosis. The most common causal gene was ABCA4, followed by USH2A and RDS/PRPH2. CONCLUSION:This study provides the first assessment of IRDs in Scotland over a 5 year period. We demonstrate that the most common clinical diagnoses are RP and Stargardt disease, and that the majority received a molecular diagnosis. This work provides a unique insight into the Scottish ophthalmic genetics service and serves as a benchmark for iterative improvement.
