This OA book presents an overview of process management, highlighting the role of all stakeholders in the process. Particularly useful for professionals and students in the field of business information systems looking for guidelines on how to discover, create, and implement real-world processes.
Atypical mitosis marks a deviation in the cell division process that has been shown be an independent prognostic marker for tumor malignancy. However, atypical mitosis classification remains challenging due to low prevalence, at times subtle morphological differences from normal mitotic figures, low inter-rater agreement among pathologists, and class imbalance in datasets. Building on the Atypical Mitosis dataset for Breast Cancer (AMi-Br), this study presents a comprehensive benchmark comparing deep learning approaches for automated atypical mitotic figure (AMF) classification, including end-to-end fine-tuned deep learning models, foundation models with linear probing, and foundation models fine-tuned with low-rank adaptation (LoRA). For rigorous evaluation, we further introduce two new held-out AMF datasets - AtNorM-Br, a dataset of mitotic figures from the TCGA breast cancer cohort, and AtNorM-MD, a multi-domain dataset of mitotic figures from a subset of the MIDOG++ training set. We found average balanced accuracy values of up to 0.8135, 0.7788, and 0.7723 on the in-domain AMi-Br and the out-of-domain AtNorm-Br and AtNorM-MD datasets, respectively. Our work shows that atypical mitotic figure classification, while being a challenging problem, can be effectively addressed through the use of recent advances in transfer learning and model fine-tuning techniques. We make all code and data used in this paper available in this github repository: https://github.com/DeepMicroscopy/AMi-Br_Benchmark
Adverse weather conditions, such as fog and rain, pose major challenges for autonomous vehicle perception by degrading sensor data quality. However, existing datasets rarely offer reproducible conditions or quantitative evaluations of sensor performance. To address this, we present MuFoRa, a multimodal dataset acquired in a controlled indoor facility using a stereo camera and two solid-state LiDAR sensors. Data were collected under clear and night conditions, as well as under simulated fog (5 m to 160 m visibility) and rain ( 20 mm h^-1 to 100 mm h^-1 ), with target distances from 5 m to 50 m. Sensor degradation is assessed using normalised image entropy for camera data and the inlier ratio of points relative to their distance from the surface of a spherical target for LiDAR data. Results show that camera performance is moderately affected by rain and strongly affected by fog, with normalised entropy dropping by 35
Perception is a cornerstone of autonomous driving, enabling vehicles to understand their surroundings and make safe, reliable decisions. Developing robust perception algorithms requires large-scale, high-quality datasets that cover diverse driving conditions and support thorough evaluation. Existing datasets often lack a high-fidelity digital twin, limiting systematic testing, edge-case simulation, sensor modification, and sim-to-real evaluations. To address this gap, we present DrivIng, a large-scale multimodal dataset with a complete geo-referenced digital twin of a 18 km route spanning urban, suburban, and highway segments. Our dataset provides continuous recordings from six RGB cameras, one LiDAR, and high-precision ADMA-based localization, captured across day, dusk, and night. All sequences are annotated at 10 Hz with 3D bounding boxes and track IDs across 12 classes, yielding 1.2 million annotated instances. Alongside the benefits of a digital twin, DrivIng enables a 1-to-1 transfer of real traffic into simulation, preserving agent interactions while enabling realistic and flexible scenario testing. To support reproducible research and robust validation, we benchmark DrivIng with state-of-the-art perception models and publicly release the dataset, digital twin, HD map, and codebase.
Deep Reinforcement Learning (DRL) has demonstrated remarkable success in autonomous decision-making across diverse domains, including robotics, autonomous driving, and game playing. However, recent studies have uncovered a critical vulnerability: DRL agents are highly susceptible to adversarial attacks that can significantly degrade their performance or lead to catastrophic failure. These attacks exploit different components of the learning pipeline observations, actions, rewards, and policies exposing new challenges unique to DRL compared to supervised learning. This survey provides a comprehensive examination of adversarial threats and corresponding defense mechanisms within the DRL paradigm. This also aims to serve as a foundational reference for researchers and practitioners seeking to understand and mitigate adversarial vulnerabilities in DRL.
