Thammasat University Hospital (Thai: โรงพยาบาลธรรมศาสตร์เฉลิมพระเกียรติ; RTGS: Rong Phayaban Thammasat Chaloem Phra Kiat) is a public hospital subsidiary to the Office of the Rector, Thammasat University, Ministry of Education. It is located in the Rangsit Campus, Pathum Thani Province, Thailand.The construction of the hospital complex began in 1986 and King Bhumibol Adulyadej presided over the ceremony of laying the foundation stone of the main building on 3 November of that year. The hospital commenced its operation on 5 December 1987, on which the king turned 60 years of age. However, the hospital was formally opened on 29 March 1988. On 19 March 1990, a royal decree was issued to establish a Faculty of Medicine in Thammasat University and the royal decree took effect as from the following day. On 10 April 1990, the hospital formally became a subsidiary of the Faculty of Medicine. On 19 February 2003, the hospital was transferred to the Office of the Rector.Apart from providing medical services to the general public, the hospital serves as a teaching hospital for the Faculty of Allied Health Science, Faculty of Dentistry, Faculty of Medicine, Faculty of Nursing and Faculty of Public Health. At present, it provides every type of medical services, receives at least 1,500 outpatients a day and has 439 beds for inpatients.The current director of the hospital is Associate Professor Chittinad Havanond (จิตตินัดด์ หะวานนท์) who has taken the office since 2014..
Background/Objectives: This study aimed to evaluate the effects of frenulotomy in mother-infant pairs with problematic tongue-tie. Methods: A 2-year prospective observational cohort study was performed. Mother-infant pairs were divided into frenulotomy and non-frenulotomy groups by maternal choice. Four breastfeeding practice outcomes were evaluated: reduced latching pain scores, improved LATCH scores, regained birth weight within 2 weeks post-partum, and successful exclusive breastfeeding (EBF) at 3 months of age. The comparison between groups was performed using multivariable risk regression with propensity score analysis. Results: A total of 350 mother-infant pairs were included. There were 226 mother-infant pairs who underwent frenulotomy and 124 pairs in the non-frenulotomy group. The median latching pain scores significantly decreased from 6 to 3 at 24 h post-operatively and from 6 to 0 at 1 week post-operatively (p < 0.001). The median LATCH scores increased significantly from 5 to 9 at 1 week post-operatively (p < 0.001). LATCH scores within 2 weeks were improved in the frenolotomy group (risk ratio = 1.31, p = 0.017). The success rate of EBF at 3 months was 72.12% in the frenulotomy group and 76.61% in the non-frenulotomy group, with no statistically significance. Conclusions: Short-term breastfeeding outcomes and LATCH scores in mother-infant pairs with tongue-tie improved faster in those who underwent the procedure, with no complications.
OBJECTIVE:Effective preoperative education is a core nursing responsibility in orthopaedic care and may influence postoperative recovery following total knee arthroplasty (TKA). This study examined the effects of a nurse-led, technology-supported preoperative education and self-care promotion program on patient knowledge and rehabilitation outcomes after TKA. METHODS:A quasi-experimental, two-group repeated-measures design was conducted among 60 patients undergoing TKA between January and August 2025. The intervention group received a nurse-led educational program delivered via the Line OA platform, incorporating e-book materials, instructional videos, and individualized nursing guidance. The control group received routine nursing care. Data were collected at pre-admission, admission, discharge, and at 2 and 6 weeks postoperatively. Outcomes included TKA-related knowledge and knee range of motion (ROM). RESULTS:Patients in the intervention group demonstrated significantly higher knowledge scores across all postoperative time points compared with the control group (p < 0.05). Knee flexion ROM showed a significant improvement over time in the intervention group, indicating enhanced functional recovery. CONCLUSION:A nurse-led, technology-supported preoperative education program improves patient knowledge and supports early postoperative rehabilitation following TKA. Integrating digital education into routine orthopaedic nursing practice may enhance patient engagement and recovery outcomes.
BACKGROUNDPreclinical studies demonstrated anti-inflammatory effects of Zingiber montanum (J.König) Link ex Dietr.(Phlai). However, its clinical effect on allergic rhinitis (AR) is not evident.OBJECTIVEWe sought to assess the efficacy and safety of Phlai for treating AR.METHODSA phase 3, randomized, double-blind, placebo-controlled study was conducted. Patients with AR were randomized into three groups and received Phlai 100 mg or Phlai 200 mg or placebo once a day for four weeks. The primary outcome was a change in the reflective total five symptom score (rT5SS). The secondary outcomes were the change in the instantaneous total five symptom score (iT5SS), the reflective individual symptom scores (rhinorrhea, nasal congestion, sneezing, itchy nose, itchy eyes), Rhinoconjunctivitis Quality of Life-36 Questionnaire (RCQ-36) score, peak nasal inspiratory flow (PNIF), and adverse events.RESULTSTwo hundred and sixty-two patients were enrolled. Compared with placebo, Phlai 100 mg improved rT5SS [adjusted mean difference (aMD) -0.62; 95%CI -1.22, -0.03; p = 0.039], rhinorrhea (aMD -0.19; 95%CI -0.37, 0.002; p = 0.048), itchy nose (aMD -0.24; 95%CI -0.43, -0.05; p = 0.011), and itchy eyes (aMD -0.19; 95%CI -0.36, -0.02; p = 0.033) at week 4. Nasal obstruction, sneezing, iT5SS, overall RCQ-36 score, PNIF did not reach statistical significance. Phlai 200 mg did not bring additional benefits compared to 100 mg. Adverse events were similar among groups.CONCLUSIONSPhlai was safe. At four weeks, there were small improvements in rT5SS, together with the individual symptoms of rhinorrhea, itchy nose, and itchy eyes.
OBJECTIVE:To identify an adequate amount of prostate chip submissions with optimal diagnostic accuracy and minimal cassette utilization for the detection of incidental prostate carcinoma (IPC). METHODS:We recruited consecutive transurethral resection specimens from patients with bladder outlet obstruction related to benign prostatic hyperplasia (BPH) and excluded patients with known or suspected prostatic carcinoma. Submission in the retrospective cohort depended on weight: either ≤12 g submitted entirely or >12 g submitted partially (initial 12 g with additional sampling). Submission was entire in the prospective cohort. The five different submissions (index test) were: initial 12 g, initial 12 g with additional cassettes per 10 g (12 g + q10 g), 12 g + q5 g, 20 g, and 20 g + q10 g. The diagnostic accuracy of the index test, compared to actual tissue submission (reference standard), was measured by the area under the receiver operating characteristic curve (AUC), with ≥95.0% considered acceptable. RESULTS:A total of 451 patients (384 retrospective and 67 prospective) were included. The specimens had a median weight of 22 (range: 1-235) g, corresponding to a median cassette use of 10 (1-48) blocks, resulting in 5,010 total blocks. The average weight per block in the prospective cohort was 2 g. IPC detection rates were 6.3% retrospectively, 9.0% prospectively, and 6.7% overall. The first cassette containing carcinoma appeared between the 1st and 24th. Only three tissue submission strategies achieved acceptable diagnostic accuracy using lower estimated cassette numbers: 12 g + q5 g: AUC 98.3%, using 4,362 blocks, 20 g + q10 g: AUC 98.3%, using 4,239 blocks, 20 g: AUC 95.0%, using 3,373 blocks. CONCLUSION:Submitting 20 g of prostatic chips offers excellent diagnostic accuracy for IPC detection with reduced cassette utilization.
Objectives This study reports a case of malleus extraction during foreign body removal and the reconstructive approach that restored hearing successfully. Results A 37-year-old woman was referred with left mixed hearing loss after a potential accidental malleus extraction during attempted cockroach removal from the external auditory canal. Otoscopic examination showed an intact tympanic membrane. Tympanometry of the affected ear demonstrated a Type Ad pattern. Pure-tone audiometry demonstrated an air-conduction threshold of 76 dB and a bone-conduction threshold of 55 dB. High-resolution temporal bone CT confirmed complete absence of the malleus with preservation of the incus and stapes suprastructure. Endoscopic middle ear exploration confirmed an intact tympanic membrane, discontinuity at the tympanic membrane–incudostapedial junction, and preservation of the stapes suprastructure with a mobile footplate. The incus was removed, and ossiculoplasty was performed using a partial ossicular replacement prosthesis (PORP) placed on the stapes suprastructure with a tragal cartilage cap beneath the tympanic membrane. Recovery was uneventful, and at 12 months the air–bone gap improved from 21 dB to 6 dB. Conclusions Malleus extraction during foreign body removal is rare but may lead to significant morbidity. Otologic procedures should be performed with caution by all practitioners. Early recognition and timely reconstruction are essential for restoring ossicular continuity and achieving optimal outcomes.
