FNA of the liver is a diagnostic test that can be used to identify the vast majority of neoplasms of a primary or metastatic nature. Well-prepared FNA samples, in conjunction with cell button preparations, and correlation with the clinical history are necessary for optimal results. Even with the best of samples, however, well-differentiated hepatocellular neoplasms, both benign and malignant, and rare lesions still can remain difficult to diagnose by FNA.
As lung transplant patients are being returned more quickly to their own communities and physicians, pathologists will be challenged more frequently to provide immediate diagnoses to distinguish infection from rejection. This chapter provides a guide for meeting this challenge and discusses in detail rejection of the graft, infection in the graft, other pathology in the graft, and the procedures for evaluating and distinguishing among these conditions.
The pathologic diagnosis of malignant mesothelioma is difficult because the disease is rare and because it has many morphologic variants. This chapter emphasizes practical aspects of the pathologic features and of the differential diagnosis of malignant mesothelioma.
The last decade has seen major advances in our knowledge of the clinical and biologic behavior of lymphomas of lung. These advances have in turn led to intriguing hypotheses that attempt to explain the origin of these lesions. In this chapter, the authors summarize the background and evolution of these intriguing lymphomas.
