We report a 53-year-old woman with laser iridotomy (LI)-resistant angle-closure and conjunctival injection, which was thought to be the cause of ciliochoroidal effusion associated with short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) syndrome. LI had no effect on any of the symptoms except for intraocular pressure. The symptoms disappeared after a subsequent procedure for SUNCT syndrome. MRI of the left eye showed ciliochoroidal effusion at paroxysm and was normalized upon relief.
Descemet's stripping automated endothelial keratoplasty (DSAEK) is an increasingly popular techniquefor transplanting corneal endothelial cells. The presence of glaucoma, and especially glaucoma tubes, however, renders the DSAEK procedure more challenging. Here, we present a case of DSAEK in a patient with quadruple glaucoma tubes.
Effectiveness of multiple subconjunctival bevacizumab injections in advanced primary pterygium was studied the first time. Treatment produced regression of pteryium and improvement of best-corrected visual acuity from 20/100 to 20/60 at 6-mont follow-up. Off-label short-term use of sbconjunctival bevaciumab is effective.
We compared the vitreous and plasma levels of proinflammatory cytokines in diabetic patients who underwent pars plana vitrectomy. Levels of proinflammatory cytokines in the vitreous were higher in the diabetic patients than the non-diabetics while the levels of plasma cytokines were similar. It is thought that this increase in the vitreous is effective in the progression of angiogenesis and the development of proliferative diabetic retinopathy.
A 35-year-old man complained of progressive exophthalmos on the left eye for six months. MRI revealed approximately 18 mm x 17 mm cyst neoplasm across the inner and outer muscle cone in the left orbital cavity. Extraction was performed. The cyst wall of the tumor had the infiltration of the cancer cells and contained the residual lacrimal gland tissue. The patient refused further cranio-orbital resection or preoperative/postoperative radiotherapy or chemotherapy. Following for nine years found no local recurrence or systemic metastasis.
We estimated serum insulin-like growth factor-1 (IGF-1) level to correlate for development of retinopathy of prematurity (ROP) in serum from 15 premature infants. 73% of the infant developed Stage 1 ROP and the rest develop Stage 2. Zone III involvement never progress beyond Stage 1, and Zone II beyond Stage 2. Severity of ROP could not be related to the level of IGF-1. All cases develop ROP of Stage 1 and 2 irrespective of serum IGF-1.
Mycosis fungoides (MF), the most common type of cutaneous T-cell lymphoma, is a low-grade lymphoma usually occurring after the age of 50 years. We present a case of a 60-year-old man with cutaneous manifestations of MF, who later developed bilateral eyelid ulceration. MF is a highly recalcitrant disease with a relentless course. Our patient highlights a delayed presentation in MF with bilateral upper lid ulcerative lesions, which responded well to systemic chemotherapy, commenced for a visceral indication.
We compared the efficacy and safety of a new fixed combination of timolol 0.5%/odorzolamide 20%/brimonidine 0.2% in ophthalmic solution versus a fixed combination of timolol 0.5%/dorzolamide 2% in patients with open-angle glaucoma or ocular hypertension. The fixed triple combination was significantly more efficient in mean intraocular pressure reduction from baseline throughout the six-month follow-up.
The efficacy of combined oral corticosteroid and low-doseoral methotrexate pulsed therapy in Eales' disease was evaluated prospectively, based on weighted visual morbidity scale for disease activity and visual acuity grading in 36 consecutive cases. Oral corticosteroids in a weekly tapering dose for 4 weeks and 12.5 mg methotrexate as a single oral dose, once per week for 12 weeks, were administered simultaneously. We concluded that this combined oral therapy is clinically effective with an acceptable safety profile.
We investigated conjunctival flora changes in vernal conjunctivitis (VC) (n = 30) patients compared to the normal eye (n = 30). Growth was observed in 86.6% of the vernal group, and 80% of the control group specimens. We believe that administering prophylactic treatment would be helpful in VC patients who are to have intraocular surgery to prevent postoperative endophthalmitis.
We describe a new surgical technique, namely, upside-down phacoemulsification and posterior chamber intraocular lens implantation combined with Descemet's stripping automated endothelial keratoplasty (DSAEK). This technique is aimed at decreasing potential complications associated with conventional phacoemulsification, including posterior lens capsular tear and vitreous loss during DSAEK and cataract surgery performed through a cloudy cornea.
A 70-year-old man right eye over 5 weeks. He was found clinically to have a bitemporal hemianopia and bilateral disc edema. Testing revealed optic nerve head drusen (ONHD) bilaterally causing enlarged blind spots (pseudo-bitemporal hemianopia). This case illustrates that ONHD should be listed in the differential diagnosis for bitemporal hemianopia when brain imaging is normal.
We report the first case of combined granular and Fuchs' corneal dystrophy in a male patient who underwent bilateral total anterior lamellar keratoplasty (TALK). Fuchs' corneal dystrophy was diagnosed after the initial diagnosis of granular dystrophy in both eyes. Total anterior lamellar keratoplasty resulted in a clear cornea and allowed visualization of the recipient corneal endothelium. Confocal microscopy following TALK revealed the presence of Fuchs' corneal dystrophy in both eyes.
We present a case of silent sinus syndrome (SSS) who underwent unilateral surgical endoscopic maxillary meatotomy. Orbital floor reconstruction is delayed after follow up. Enophthalmos recovered 8 months after the surgery and radiologic findings improved. SSS is a clinical entity that should be kept in mind in the differential diagnosis of enophthalmos and can be treated successfully via endoscopic approach.
Clinicians are confronted with a plethora of new machines, new software, and new applications of technology, all intended to help with glaucoma management. It is helpful to return to basic principles, to see how these advances fit into our assessment of the intraocular pressure, optic nerve, and visual fields.
We compared the ability to discriminate between healthy and glaucomatous eyes of three optical imaging devices in 140 eyes from 140 subjects. No statistically significant differences were found among the AUCs of these parameters. However, AUCs were significantly higher in OCT and HRT parameters than most of GDx VCC ones. Thus, structural parameters assessed by the optical imaging devices are useful to discriminate glaucomatous damage, but showed no significant difference among the best parameters from HRT, OCT or GDx VCC.
We report a 61-year-old who developed candidemia following pancreatic tumor surgery, and presented with bilateral multifocal chorioretinitis and vitritis. Chorioretinal lesions regressed with fluconazole therapy. Pars plana vitrectomy was performed with resultant improved visual acuity, but vitritis recurred with the next chemotherapy session. With the cessation of chemotherapy, vitritis regressed without any systemic treatment.
