We compared the ability to discriminate between healthy and glaucomatous eyes of three optical imaging devices in 140 eyes from 140 subjects. No statistically significant differences were found among the AUCs of these parameters. However, AUCs were significantly higher in OCT and HRT parameters than most of GDx VCC ones. Thus, structural parameters assessed by the optical imaging devices are useful to discriminate glaucomatous damage, but showed no significant difference among the best parameters from HRT, OCT or GDx VCC.
We evaluated the diagnostic ability of various diagnostic tools to detect glaucomatous damage in 101 normal eyes and 102 glaucomatous eyes. Mikelberg’s linear discriminant function (LDF) obtained the best sensitivity followed by our own four formulas. With respect to specificity, Burk’s LDF showed better results than Mikelberg’s LDF and our formulae. Several Heidelberg retina tomograph analysis tools are useful to discriminate healthy from patients with glaucoma. Alternative tools based on normaltive databases derived from different autochthon populations add evidence needed to support their global use.