ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION:Shetty, S., Errichetti, A., Narasimhan, S., Al-Daghestani, H., & Shetty, G. The use of virtual reality and haptics in the training of students in restorative dentistry procedures: a systematic review. Korean J Med Educ. 2025;37:203-217. SOURCE OF FUNDING:This research received no specific grant from any funding agency in the public, commercial, or not-for profit sectors. TYPE OF STUDY/DESIGN:Systematic review (SR).
Over the past quarter-century, pediatric dentistry has shifted from an expert-opinion-driven craft-often extrapolated from adult dental care, to become a discipline anchored in rigorous, child-specific evidence. This transformation reflects the maturation of evidence-based dentistry (EBD): integrating the best available research with clinical expertise and the values and preferences of children and their families. As we celebrate the Journal of Evidence-Based Dental Practice at 25years of age, this article charts some milestones in pediatric EBD that show how clinical practice has led to scientific enquiry, research investigations and widespread changes in practice. The examples used are the Hall Technique, Atraumatic Restorative Treatment and pulp canal obliteration in dental trauma management. A pathway to improve research impact is proposed, stretching from ensuring research relevance and methodological rigor through to talking and listening to those who are stakeholders, planning implementation of findings, using core- and patient relevant- outcome sets, public communication and open science. Change does not have to be global to be important: locally tailored, context-aware research and its implementation can improve children’s oral healthcare, reduce inequalities and deliver value. This article is part of the special issue "Celebrating 25 Years of the Journal of Evidence-Based Dental Practice".
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION:Effects of disinfectants on physical properties of denture base resins: A systematic review and meta-analysis. Zhang K, Zhang S, Shi Y, Zhang L, Fu B. J Prosthet Dent. 2024;131(5):841-858. SOURCE OF FUNDING:Not reported. TYPE OF STUDY/DESIGN:Systematic review with meta-analysis of data.
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION:Impact of maxillary expansion on the sagittal skeletal and dental parameters of growing Class II patients: A systematic review with meta-analysis. Cannatà D, Galdi M, Scelza C, Simeon V, Giordano F, Martina S. Orthod Craniofac Res. 2025 Feb;28(1):116-132. SOURCE OF FUNDING:None. TYPE OF STUDY/DESIGN:Systematic review with meta-analysis.
Background and Objectives Tele-dentistry combines telecommunications and dentistry to transmit clinical data for remote consultation and treatment planning. It improves dental care access for screening, referrals, and treatment. This study aimed to test the accuracy of intraoral camera and smartphone camera in the diagnosis of cavitated carious lesions among adults in Alexandria, Egypt. Methods A diagnostic accuracy study was conducted on adults above 18 years old visiting clinics of the Faculty of Dentistry, Alexandria University to compare 2 different tele-dentistry caries detection methods (intraoral camera (C50 Full HD with fluorescence) and smartphone camera (Samsung Galaxy A24) after randomizing the participants into 2 groups. The reference standard was face-to-face examination. The caries diagnosis was based on the International Caries Detection and Assessment System (ICDAS) through clinical examination, intraoral camera videos, and smartphone photos. Sensitivity, specificity, accuracy, positive and negative predictive values were calculated for the 2 methods at tooth and surface levels. Results The study included 50 adults. The age group (26-40) comprised (46%) of the participants. Both cameras had high specificity and accuracy (>90%). The lowest sensitivity was in the case of detecting cavitated lesions at surface level (intraoral camera = 84.62% and smartphone = 79.52%). The smartphone camera had the lowest precision at both tooth (49.3%) and surface (58.4%) levels." Conclusion The intraoral camera showed higher accuracy than the smartphone camera especially in detecting cavitated carious lesions at surface level. While intraoral cameras are the preferred modality, smartphone cameras provide a more accessible and cost-effective alternative, especially in resource-limited settings. However, their limitations should be acknowledged.
Objectives To evaluate the efficacy of intensive application of Curodont Repair Fluoride Plus (CRFP), MI varnish or Duraphat in treating white spot lesions (WSLs) of primary teeth over 12-months follow-up. Methods Sixty-six high-caries-risk preschooler children with active WSLs in their primary anterior teeth, were randomly allocated to receive intensive application of CRFP, MI varnish, or Duraphat. Lesions were assessed using ICDAS-II criteria and DIAGNOdent laser fluorescence at baseline and after 3, 6, 9, and 12 months. lesion size changes were evaluated using standardized photographs after 3, 6, and 12 months. Visual analogue scale was used for assessing esthetic improvement after 6 and 12 months. Results Multivariable logistic regression models addressing caries arrest (using ICDAS-II severity scores) and reducing lesion activity revealed that CRFP achieved significantly higher odds of caries arrest (AOR=6.46, P = .011) and decreasing number of active lesions (AOR=19.86, P = .003) when compared to Duraphat. No significant difference was found between MI varnish and Duraphat regarding caries arrest (AOR=2.07, P = .242) or reducing lesion activity (AOR=4.11, P = .064). All study materials resulted in significant percent reduction in DIAGNOdent readings across time (P < .001). CRFP reduced DIAGNOdent readings significantly when compared to Duraphat at all time intervals while a significant difference appeared between CRFP and MI varnish groups only after 9 and 12 months. All the materials reduced lesion size significantly, with the greatest reduction achieved by CRFP, resulting in moderate to exceptional esthetic improvement. Conclusion Intensive application of CRFP exhibited superior remineralization and esthetic improvement of WSLs compared to MI varnish or Duraphat.
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION:Aldrin Huamán-Mendoza, Renata Bommarito, Marcos Hideki Hagy, Nathalia Vilela, Marcelo Munhóes Romano, Mariana Minatel Braga, Claudio Mendes Pannuti, Marinella Holzhausen. Effect of laser-microtextured abutments on peri-implant outcomes: a systematic review and meta-analysis. Clinical Oral Investigations (2024) 28:388 https://doi.org/10.1007/s00784-024-05785-1 SOURCE OF FUNDING: This research received no specific grant from any funding agency. TYPE OF STUDY/DESIGN:Systematic review with meta-analysis.
Objectives This study aimed to identify baseline factors that predict Health-Related Quality of Life (HRQoL) in patients with TMD 8 years later. Materials and Methods 401 participants (333 women, mean age 45.8 years) from a multicenter cohort were examined using the Diagnostic Criteria for TMD (DC/TMD) and questionnaires. The main outcome was the 12-item Short Form Health Survey (SF-12), a HRQoL measure that provides physical (PCS) and mental (MCS) summaries. Baseline predictors included age, gender, self-reported health, Jaw Functional Limitation Scale (JFLS), pain intensity, pain frequency, and pain duration. Regression analysis with stepwise modeling identified predictive factors. Results 54.3% had painful TMD, 15.7% had nonpainful TMD, and 27.7% were healthy controls. For the painful TMD group, the regression model was significant (R² = .25, F = 4.3, P < .01), with age and favorable general health predicting PCS scores. In the nonpainful TMD group, the model was significant (R² = .58, F = 3.8, P < .01), with JFLS and favorable general health (predicting PCS scores. The MCS model was significant in healthy controls (R2 = .22, F = 1.8, P = .05), with JFLS as only predictor. Conclusion Predictors of mental HRQoL: JFLS in healthy controls, but no predictors were found in TMD groups. Predictors of physical HRQoL: General health in both TMD groups, JFLS in the nonpainful TMD group, and age in the painful TMD group.
OBJECTIVES:This study aimed to assess the efficacy and safety of adding single-dose preemptive celecoxib 200 mg (Cc) or tramadol 37.5 mg/acetaminophen 325.0 mg (T/A) to standard postoperative analgesia after impacted mandibular third molar extraction, a design not previously explored. METHODS:In this multicenter, prospective, randomized, double-blind, placebo-controlled, crossover within-subject study, participants were randomly assigned to 2 groups (Cc or placebo for group A; T/A or placebo for group B) and underwent impacted mandibular third molar extraction on both sides at 1-month intervals. Along with baseline characteristics, pain intensity in Visual Analogue Scale (VAS), first perceived pain occurrence, rescue medication use, and adverse events were evaluated. RESULTS:A total of 33 participants per group completed the trial. Cc reduced pain at 3 (-0.91 ± 2.17; P = .011) and 6 hours (-0.85 ± 2.24; P = .018), while T/A reduced pain at 1 (-1.40 ± 2.37; P < .001), 2 (-0.79 ± 2.32; P = .030), and 6 hours (-0.91 ± 1.94; P = .006) postextraction, with some insignificant reductions at other times. Both Cc and T/A were effective in reducing the first perceived pain. Notably, Cc significantly decreased pain intensity, T/A significantly delayed the pain perception. Both drugs had no significant effect on the need for rescue medication or adverse event rates. CONCLUSIONS:Based on these results, both Cc and T/A appears to aid in reducing postoperative pain following impacted mandibular third molar extraction without significant adverse effects.
OBJECTIVE:To assess the effectiveness of an intervention on caregivers' assisted toothbrushing techniques and oral health maintenance for preschool-aged children, and to determine whether these effects differ by age. METHODS:A single group pre/post intervention study was conducted among children aged 3-5 years and their caregivers in Callao, Peru. Eligible caregivers were trained on assisted toothbrushing using large and real-scale typodonts, along with practical demonstrations by a dentist. Additionally, they were instructed on healthy practices and oral health in children. Children's oral hygiene status (OHS) was assessed using the Simplified Oral Hygiene Index (OHI-S) at baseline and three months postintervention. To assess the effectiveness and quantify the magnitude of the difference between the OHI-S before and after the intervention, we used Wilcoxon signed-rank test and the Cliff's Delta test, respectively. Results were stratified by age group to examine potential differences. RESULTS:The sample (n = 210) predominantly comprised 3-year-old Peruvian females, primarily cared for by their mothers, who identified as single mothers who had not previously received instruction in oral hygiene practices. We found improvement in children's OHI-S in most age groups. Specifically, among 3-year-olds, the OHI-S score improved significantly from 'fair' (m = 2.6, ± 0.2, range 2.4-2.8) to 'good' (m = 1.1, ± 0.2, range 0.9-1.3). The intervention showed a moderate effect size (δ = -0.15, 95% CI -0.18, -0.10) in the 3-year-olds and a moderate effect size (δ = -0.05, 95% CI -0.08, -0.01) in the 4-year-olds. No significant improvements were observed in the 5-year-old group. CONCLUSION:A caregiver-focused intervention significantly improved OHS among preschool-aged children, particularly in younger age groups. Substantial improvements in OHI-S scores were noted for 3- and 4-year-olds, while age-specific factors may have limited efficacy in the 5-year-old group. These findings highlight the importance of early, targeted oral health education for caregivers.
Article Title and Bibliographic Information Glossop S, Duffaydar H, Jones H, Peters E, Ryan T, Saleh F, Scourfield L, Poacher A. Oral and maxillofacial surgery and dental health education in undergraduate medicine: a systematic review. B J Oral Maxillofac Surg. 2024:62;882-888.1 Source of Funding Not applicable. Type of Study/Design Systematic review (SR).
Background Hypersensitivity from Molar Incisor Hypomineralisation (MIH) negatively affects children's oral health-related quality of life (OHRQoL). Aim To evaluate and compare the effectiveness of photobiomodulation (PBM) by low-power laser, resin-based (Fisseal), and glass ionomer (Fuji TRIAGE) sealants on hypersensitivity in children with MIH and their impact on OHRQoL. Design Forty-five children aged 6-10 with one first permanent molar affected by MIH and hypersensitivity were randomly assigned to 3 groups: Group 1 (n = 15) PBM, Group 2 (n = 15) Fuji TRIAGE, and Group 3 (n = 15) Fisseal. Hypersensitivity was assessed before and 15 minutes postintervention, with follow-ups at 1 week, and 1, 3, and 6 months. Pain and sensitivity were measured using the Wong-Baker Faces Pain Rating Scale (FPS) and the Schiff Cold Air Sensitivity Scale (SCASS). OHRQoL was evaluated with the Child Perceptions Questionnaire (CPQ8-10). Results No significant differences in SCASS or FPS scores were found between groups. Significant reductions in SCASS and FPS were observed over time (P < .001), with PBM and Fisseal showing notable FPS improvements at 6 months. All groups showed significant OHRQoL improvements (P < .001), particularly Fisseal. Conclusion Both glass ionomer and resin-based sealants and PBM are effective in reducing hypersensitivity associated with MIH. Clinical Significance PBM is a noninvasive therapy for managing hypersensitivity in children with MIH offering an alternative for apprehensive patients.
Objectives To evaluate the efficacy of Hy-N spray in dry mouth patients. Materials and Methods A randomized double-blind crossover study was conducted on patients with dry mouth. They were given 3 saliva substitute sprays: Hy-N, placebo, and Biotène. The unstimulated whole saliva flow rate (UWSFR), salivary pH, and xerostomia questionnaire (XQ) were evaluated at baseline and after 1 week of treatment with each spray. Patient satisfaction was evaluated after each treatment period. Results Twenty-nine patients completed the study. After using the Hy-N and Biotène sprays for 1 week, the UWSFR significantly increased from 0.12 ± 0.16 at baseline to 0.16 ± 0.18 mL/min postspray usage (P = .04, P ≤ .01) with moderate improvement. None of the sprays affected salivary pH (P = .72). The mean XQ score also significantly decreased from 34.2 ± 21.4 at baseline to 23.7 ± 17.4, 23.1 ± 15.2, and 26.5 ± 17.7 after using Hy-N, Biotène, and placebo spray, respectively (P = .001, P = .011, P = .009) with moderate improvement. Biotène was the most preferred saliva substitute spray, followed by Hy-N spray. Conclusion Using the Hy-N and Biotène for 1 week relieves subjective and objective dry mouth. They can be a useful product in the management of dry mouth without causing side-effects.
OBJECTIVES:Molar-incisor hypomineralization (MIH) can cause hypersensitivity. This study compared nanosilver fluoride (NSF) and photobiomodulation therapy (PBMT) regarding desensitization in MIH-affected first permanent molars (FPMs) and plaque reduction. METHODS:Children aged 7-10 years, with 120 hypersensitive MIH-affected FPMs, were randomly assigned to receive NSF or PBMT. Hypersensitivity was assessed using the Schiff Cold Air Sensitivity Scale (SCASS) at baseline, after 15 minutes and 1 month. Plaque accumulation was assessed using the modified plaque index (PlI) of Silness and Löe at baseline and after 1 month. T-test and Mann-Whitney U test were used to compare groups. Intragroup comparisons were done using paired t-test and Friedman test. Multilevel ordinal logistic regression analysis was used to assess the effect of treatment on the outcomes, controlling for confounders. RESULTS:The study included 40 children, mean ± SD age = 8.03 ± 1.13 years. There was significantly less sensitivity and greater plaque reduction in the NSF than the PBMT group after 1 month (P < .05). NSF and PBMT significantly reduced sensitivity over time (P < .001), with the lowest scores after 1 month. In multilevel regression, NSF was associated with significantly less sensitivity than PBMT after 1 month (AOR = 0.18, 95% CI: 0.07, 0.51, P = .001). While both groups had reduced plaque accumulation, the decrease was significant only in the NSF group (P < .001). CONCLUSION:NSF and PBMT reduced sensitivity associated with MIH and provided immediate pain relief. However, NSF was superior due to its longer-lasting effects on sensitivity and additional benefit in plaque reduction. CLINICAL SIGNIFICANCE:NSF offers a promising alternative to PBMT in desensitizing MIH-related hypersensitivity, particularly for patients with limited access to laser therapy. TRIAL REGISTRATION:The trial was registered in the clinicaltrials.gov registry (# NCT06348849).
Article Title and Bibliographic Information Camps-Font O, Sábado-Bundó H, Toledano-Serrabona J, Valmaseda-de-la-Rosa N, Figueiredo R, Valmaseda-Castellón E. Antibiotic prophylaxis in the prevention of dry socket and surgical site infection after lower third molar extraction: a network meta-analysis. Int J Oral Maxillofac Surg. 2024;53(1):57-67. Source of Funding None declared. Type of Study/Design Systematic review with network meta-analysis.
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION:Chen Y, Alhozgi AI, Almeida FR. Dentoskeletal changes of long-term oral appliance treatment in patients with obstructive sleep apnea: A systematic review and meta-analysis. J Prosthodont 2024 (In eng). DOI: 10.1111/jopr.13946. SOURCE OF FUNDING:No financial support was obtained for this study. TYPE OF STUDY/DESIGN:Systematic review and Meta-Analysis.
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION:Artificial intelligence-driven automation of nasoalveolar molding device planning: A systematic review. Alqutaibi AY, Hamadallah HH, Alassaf MS, Othman AA, Qazali AA, Alghauli MA. J Prosthet Dent. 2024 Oct 4:S0022-3913(24)00637-1. doi: 10.1016/j.prosdent.2024.09.011. Epub ahead of print. PMID: 39368883. SOURCE OF FUNDING:This research did not receive any grant from any funding agency in the public, commercial, or not-for- profit sectors. The authors declared that they had no financial interests or personal relationships that could influence the work reported in the study. TYPE OF STUDY/DESIGN:Systematic Review.
OBJECTIVES:to evaluate the clinical effectiveness of 1% dimethyl-sulfoxide (DMSO/H2O) dentin pretreatment on the clinical performance of 2-step etch-rinse adhesive after 36-months of a follow-up. METHODS:Twenty-nine patients with 82 non carious-cervical lesions NCCLs were eligible for the study. NCCLs were randomly distributed into 2 equal groups. Both groups were acid etched then bonded with (Single-bond2, 3M-ESPE) and restored with a nanohybrid composite (Z350XT, 3M-ESPE) under rubber-dam isolation. Only for the intervention group 1% DMSO/H2O was applied for 60s then blot dried after etching and before bonding. The restorations were evaluated at baseline, 12-, 24-, and 36-months using FDI criteria for evaluation of the restoration. For the statistical analysis, intergroup comparison between interventions was performed using Chi-Square-test (P ≤ .05), intragroup comparison within each intervention was performed using the Cochran's Q-test (P ≤ .0083). RESULTS:In the current study, intergroup comparison between both groups at baseline and after 12, 24 and 36 months showed no statistically significant differences for all tested outcomes (P > .05), except for marginal discoloration at 36 months, where there was statistically significant difference (P < .05) favoring DSMO. Intragroup comparison within control revealed statistically significant deterioration through time (P < .001) for all tested parameters, also within DSMO there was statistically significant change through time (P < .0083). CONCLUSION:The clinical performance of a 2-step etch-rinse adhesive in combination with 1% DMSO pretreatment was better than the control without pretreatment. Longer follow-up and higher concentrations of DMSO pretreatment should be evaluated in the future. CLINICAL SIGNIFICANCE:Several laboratory studies showed that DMSO pretreatment improves the hybrid layer quality and integrity. However, this clinical trial gave the proof of the clinical effectiveness of this protocol after 36-months follow-up.
Article Title and Bibliographic Information Orthodontic correction of anterior open bite using skeletal anchorage: systematic review and meta-analysis. Kwon TG, Elnagar MH, Shirazi S, Goben AH, Miloro M, Han MD. Int J Oral Maxillofac Surg. 2024 May;53(5):393-404. Source of Funding The authors did not report funding for this investigation. Type of Study/Design Systematic Review with Meta-Analysis.
BACKGROUND:Antibacterial ingredients for oral care products are typically measured through single product forms. This study assessed the overall health outcome of using multiple forms: a stabilized stannous fluoride toothpaste, an enhanced cetylpyridinium chloride mouthwash and a unique toothbrush to deliver antibacterial performance. METHODS:A 12-week, single-center, phase III, masked, 2-arm, parallel-group, randomized controlled trial was conducted to assess the reduction of established dental plaque and gingivitis with a novel antibacterial oral regimen comprised of 0.454% stannous fluoride toothpaste stabilized with nitrate and phosphates, 0.075% cetylpyridinium chloride and 0.28% zinc lactate mouthwash, and rapid foaming manual toothbrush compared to a nonantibacterial commercially available regimen of toothpaste containing 0.76% sodium monofluorophosphate, no mouthwash, and commercially available manual toothbrush to represent standard toothbrushing practices. RESULTS:Adherence to this novel oral care regimen provided significant reduction in plaque and gingivitis compared to the control starting at 1 week (P < .01) and continuing over 12 weeks (P < .001) across all plaque and gingival score indices. At week 1, participants in the Antibacterial Regimen Group showed 15 times more plaque reduction than control (P < .001). After 3 weeks of regimen adherence, 100% of Antibacterial Regimen participants had improved gingival index scores compared to baseline. CONCLUSIONS:Within the limitations of the study, the results showed statistically significantly reduced gingival inflammation and improved plaque control from 1 week continuing through 12 weeks of adherence to this novel oral care regimen compared to standard toothbrushing practices.
