Objective:To explore the rehabilitation effect of Tai Chi Yunshou combined with robot-assisted training on hand function of stroke pa-tients.Method:A total of 60 stroke patients were selected and randomly divided into a treatment group(n=30)and a control group(n=30).Both groups received conventional rehabilitation therapy.The treatment group received Tai Chi Yunshou training combined with robot-assisted training,the control group received robot-assisted training.The training frequency of the two groups was 60min/day,5 days/week,and the treatment continued for 8 weeks.Before treatment,after 4 weeks of treatment,and after 8 weeks of treatment,the Fugl-Meyer motor function scale(FMA)wrist-hand part,the Wolf motor function test(WMFT),Box and Block Test(BBT),grip strength and pinch strength to assess the hand function.Result:The dif-ference between the two groups of patients after treatment and before treatment was statistically significant(P<0.001).There was no statistically sig-nificant difference between the groups after 4 weeks of treatment(P>0.05).After 8 weeks of treatment,the difference in WMFT between the groups was statistically significant(P>0.05).FMA wrist-hand part,BBT,grip strength and pinch strength were not statistically different(P>0.05).Conclu-sion:Tai Chi Yunshou combined with robot-assisted training can improve hand function in stroke patients.
Objective:To analyze the rehabilitation needs and the associated factors of individuals with spinal cord injury(SCI)in Shanghai.Meth-ods:The participants were individuals with SCI from permanent Shanghai families who participated in rehabilitation training at Shanghai Sunshine Rehabilitation Center.The evaluation table of community-based rehabilitation demand of individuals with SCI developed by our research team,Com-munity Integration Questionnaire(CIQ),EQ-VAS,Zung self-rating anxiety/depression Scale(SAS/SDS)and a self-designed questionnaire were used.Descriptive statistics,reliability and validity analysis,and multiple logistic regression were employed in statistical analysis.Results:A total of 280 individuals with SCI were included in the study,of which 65 participated in the test-retest study.The evaluation table of community-based reha-bilitation demand showed good internal consistency,test-retest reliability,and content and structural validity.Exploratory Factor Analysis revealed that the 15 assessment items could be categorized into four need dimensions:education/employment,social,empowerment and health.The overall level of community rehabilitation needs was 64.6%,with education/employment needs(55.3%)and social needs(58.4%)scoring lower than 60%.The percentages of the seven need items were lower than 50%:cultural and artistic activities(34.7%),psychological counselling(35.0%),informal education(35.3%),formal school education(41.9%),sports activities(43.6%),employment and entrepreneurship(43.7%),and entertainment and lei-sure activities(48.6%).The multivariate analysis found that individuals with high school or lower education level(OR=2.20)and those from other provinces/cities(OR=2.06)had higher possibilities to demand psychological counselling compared to those with a higher education background and Shanghai Hukou residents.The participants who had been enrolled in 2018-2019(OR=3.21),had a college degree or above(OR=2.31),and acted as community rehabilitation instructors(OR=2.10)were associated with higher proportions of informal education needs compared to those who had been enrolled in 2020,had a high school education background or below,and were normal individuals with SCI.Unmarried/divorced/widowed partic-ipants(OR=2.24)and those who were employed/students(OR=2.12)were more inclined to pursue formal education compared to the married or un-employed participants.The participants who were from other provinces/cities(OR=2.72),those aged under 50 years(OR=2.84),and with a monthly income below 6000 yuan(OR=3.63)had a higher possibility to demand employment and entrepreneurship compared to participants with Shanghai Hukou,those aged over 50 years,and those with a monthly income above 6000 yuan.Community rehabilitation instructors(OR=4.73 and 2.99)and females(OR=1.83 and 2.49)had greater needs for cultural and artistic activities,and sports activities compared to normal individuals with SCI and the males,respectively.The participants with more than 10 years of injury history(OR=1.72)had a higher percentage of cultural and artistic activities needs,while the participants with complete injury had a high possibility of needing sports activities compared to those with incomplete injury(OR= 1.90).Conclusion:The community rehabilitation needs of individuals with SCI from permanent Shanghai families were at a medium level,with em-powerment and health needs being at a high level,and education/employment and social needs being at a relatively low level.
Objective:To explore the repair effect of tuina on overuse-induced skeletal muscle injury in rats and the effects of Hippo signaling path-way and myogenic regulatory factors.Methods:Twenty-four male SD rats were randomly divided into control group(C group),model group(M group),model + tuina group(T group)and model + sham tuina group(G group),with 6 rats in each group.EIMD model was established by 4-week heavy load exercise in group M,T,G;Group T was treated with tuian by pressing 6 hours after exercise,and Group G was treated with brush at the same time.Ultrastructural changes of muscle fibers were observed by transmission electron microscope,cross-sectional area of muscle fibers was evaluated by HE staining,mRNA expression of MST1,YAP,TAZ,TEAD2 was detected by real-time quantitative RT-PCR,and expression of PAX7,MYOD,MYOG protein was detected by Western Blot.Results:(1)Behavioral results showed that the ratio of grasping force/body mass of limbs in-creased and CSA decreased in model group and sham push group(P<0.05).Tuina could further increase the ratio of grasping force/body mass of limbs and increase CSA(P<0.05);Transmission electron microscope showed that muscle fiber sarcomere swelling,Z-line rupture and cell arrange-ment disorder in model group and sham tuina group.Tuina promoted muscle fiber repair to a certain extent;The expression of YAP,TAZ,TEAD2 mRNA decreased and the expression of MST1 mRNA increased in model group and sham tuina group,but the expression of YAP,TAZ,TEAD2 mRNA increased and the expression of MST1 mRNA decreased(P<0.05);The expression of PAX7,MYOD protein decreased and the expression of MYOG protein increased in model group and sham tuina group.Tuina increased the expression of PAX7,MYOD protein and decreased the expres-sion of MYOG protein.Conclusion:tuina can effectively promote the benign repair of overused muscle injury,and the mechanism may be related to the regulation of hippo signaling pathway and myogenic regulatory factors.
Massage is a commonly used therapeutic technique in clinical massage,which has the effects of relaxing tendons and unblocking collater-als,activating blood circulation and removing blood stasis,relieving swelling and pain,eliminating accumulation and guiding stagnation,and calm-ing the heart and mind.Finger kneading and palm kneading are widely used in clinical practice.Based on the relevant clinical literature in recent ten years,this paper briefly describes the current application of kneading in pain,internal medicine,gynecology,pediatrics,providing reference for ex-panding the clinical application of kneading.
Objective:By pre-column derivatization to establish a gas chromatography-mass spectrography method for determination of protential metabolic biomarkers,and was used to study the metabolic changes in the plasma of experimental hyperlipidemia rats.Methods:SD rats were ran-domly divided into normal control group and experimental hyperlipidemia model group.The experimental hyperlipidemia rat model was reproduced by feeding with high-fat diet.Orbital blood was taken and pre column derivatization was performed.The analytical method was established by GC-MS and investigated for methodology,including precision,reproducibility and stability.The plasma samples of normal control group and experimen-tal hyperlipidemia group were detected,and the potential metabolic markers were identified.Results:A metabonomic method based on GC-MS was established for the analysis of experimental hyperlipidemia plasma.The RSD of the relative peak areas in the precision,repeatability and stability tests of the method were less than 10%.Conclusion:The method is rapid,accurate,reproducible,and can be used for the determination of endog-enous metabolites in plasma of rats with hyperlipidemia.The method can provide some reference for the application of metabonomics in hyperlipid-emia.
