Chiari type I malformation (CM-1) is a birth defect where the back part of the skull does not develop properly, leading to the formation of a small and shallow space at the back of the head. The aim of this case series is to determine the causes and pathologies associated with Chiari type 1 malformation and the possible management and treatment, as well as the best outcomes that aid in the postoperative evolution of CM-1 decompression.
The sacroiliac joints are among the largest joints in the human body. They are subjected to heavy loads on a daily basis. The pathology of the sacroiliac joints can be easily missed due to the many common and overlapping symptoms with other diseases in this area. The thin joint capsule, the high mechanical load, and the asymmetrical movement of the pelvic girdle explain the frequent involvement of the sacroiliac joint. Chronic degenerative processes in the joint may result from rheumatic, infectious, drug-dependent and oncological causes. Diseases such as ankylosing spondylitis, psoriatic arthropathy, Bechet’s disease, hyperparathyroidism and various pyogenic causes also cause changes in the joint. Hormonal changes during pregnancy and being overweight are predisposing factors for the development of chronic sacroiliac arthritis. According to the literature, 10-25% of the pain in the area is due to sacroiliac joint pain. Due to the often irradiating pain in different directions, a correct diagnosis is difficult. The therapy of chronic sacroilitis is continuously improving due to the high social importance of this disease. Twenty-eight patients were treated in the Department of Neurosurgery of Pulmed University Hospital with hyaluronic acid injection and corticosteroid blockade, under X-ray control in both sacroiliac joints. Preoperatively, the patients were evaluated using neurological examination and the Oswestry Disability Index, VAS, and “Facial Pain Rating Scale” scales. The results after the minimally invasive methodology showed an excellent response to the pain syndrome. Follow-up of the patients continued up to nine months after the manipulation.
Objective. Acute pulmonary embolism (APE) is a life-threatening condition and represents the third most common cause of cardiovascular mortality. Computed tomography pulmonary angiography (CTPA) is considered the gold standard for the diagnosis of APE. The primary aim of this retrospective study was to investigate the association between admission laboratory markers in patients with CTPA-confirmed APE and the level of clot burden, as assessed by the modified Qanadli score (mQS), which should not be underestimated as a potential prognostic predictor.
Artificial intelligence (AI) is reshaping healthcare by enhancing diagnostic precision, treatment personalization, and overall patient care. By leveraging technologies such as machine learning, deep learning, natural language processing, and computer vision, AI enables faster and more accurate decision-making, supports drug discovery and development, and facilitates remote patient monitoring. Beyond improving clinical outcomes, AI also contributes to holistic well-being by addressing physical, mental, social, occupational, and environmental health. Wearable AI devices promote proactive health management, virtual assistants improve mental health accessibility, and predictive analytics enable early intervention for disease prevention. However, the integration of AI in healthcare presents challenges, including data privacy concerns, algorithmic bias, and the need for transparency and trust. Ensuring the responsible and equitable deployment of AI requires robust ethical guidelines, interdisciplinary collaboration, and policies that safeguard patient rights while maximizing the technology’s benefits. By exploring both the transformative potential and inherent challenges of AI, this paper aims to highlight the critical role of AI in shaping the future of healthcare and human well-being.
Cleft lip with or without cleft palate is the most common congenital malformation of the head and neck. Children with cleft anomalies may experience a multitude of physical and developmental challenges. Psychosocial and emotional concerns of the patients and their families can also occur. As such, comprehensive care for the patient with cleft lip and/or palate requires an interdisciplinary team. This article describes epidemiology, embryo-logical developmental processes, known environmental and genetic risk factors, and their interaction, the assessment and current treatment recommendations for children born with cleft lip and/or cleft palate. We review the commonly used surgical techniques for repair, clinical outcomes and complications. Throughout the discussion, we share our experience and identify areas for future study with the focus on cleft palate management.
