目的 分析实时荧光定量PCR检查对宫颈癌早期筛查的临床价值.方法 选取苏州大学附属第二医院486例进行宫颈癌早期筛查的受检者为研究对象,以组织活检结果为金标准,分析实时荧光定量PCR检查的诊断效能.结果 486例受检者中宫颈癌早期筛查阳性82例(16.87％),其中CIN Ⅱ、CIN Ⅲ、宫颈癌分别为7例、40例、35例;阴性404例(83.13％),其中宫颈炎、CIN Ⅰ分别为320例、84例.②以组织活检结果为金标准,实时荧光定量PCR检查的诊断准确率为58.02％、敏感度为84.15％、漏诊率为15.85％、特异度为52.72％、误诊率为47.28％.实时荧光定量PCR检查宫颈病变类型的准确性较低,一致性不理想.结论 实时荧光定量PCR检查对宫颈癌早期筛查有一定临床意义,敏感度较高,但仍存在一定的误诊和漏诊,且宫颈病变类型鉴别效果不理想,因此还需联合其他检查,进一步提升准确率.
目的 了解子痫前期(PE)患者剖宫产术后的睡眠状况并分析其影响因素.方法 选取139例行剖宫产分娩的PE患者,根据患者术后的匹兹堡睡眠质量指数(PSQI)测评有无发生睡眠障碍分为睡眠障碍组和睡眠正常组,对两组资料进行单因素分析,然后通过多因素Logistic回归分析筛选出影响PE患者剖宫产术后睡眠的显著因素.结果 139例PE患者剖宫产术后PSQI评分为(11.06±2.69)分.PSQI总分＞7分为74例(睡眠障碍组)、≤7分为65例(睡眠正常组).睡眠障碍组与睡眠正常组在紧急剖宫产、术后医院焦虑抑郁量表(HAD)评分、术后视觉模拟评分法(VAS)评分、喂养方式指标比较,差异有统计学意义(P＜0.05).多因素Logistic回归分析表明:紧急剖宫产、术后HAD评分高、术后VAS评分高、纯母乳喂养均是PE患者剖宫产术后睡眠的影响因素(P＜0.05).结论 PE患者剖宫产术后睡眠质量差,其中紧急剖宫产、HAD评分高、VAS评分高、婴儿喂养均是其睡眠差的影响因素.
Objective To explore the endocrine characteristics of infertility patients with obese polycystic ovary syndrome(PCOS).Methods 64 obese PCOS patients with infertility were selected as the study objects.According to their body mass index(BMI),they were divided into obese group(BMI＞24 kg/m2)and non-obese group(18.5～24 kg/m2),with 32 cases in each group.Chemiluminescence immunoassay and radioimmunoassay were used to detect the clinical indexes of the two groups.Anthropometric index,sex hormone and blood lipid levels were compared between the two groups.Results The weight,BMI,hip circumference,waist circumference and waist-to-hip ratio in the obese group were higher than those in the non-obese group,with statistical significance(P＜0.05).The levels of total testosterone(TT),total cholesterol(TC),triglyceride(TG)and fasting insulin(FINS)in the obese group were higher than those in the non-obese group,while the levels of sex hormone binding globulin(SHBG),luteinizing hormone(LH),estradiol(E2),progesterone(P)and prolactin(PRL)in the obese group were lower than those in the non-obese group.The difference was statistically significant(P＜0.05).There was no significant difference in the levels of dehydroepiandrosterone sulfate(DHEAS),follicle-stimulating hormone(FSH),high density lipoprotein cholesterol(HDL-C)and low density lipoprotein cholesterol(LDL-C)between the two groups(P＞0.05).Conclusion Obese PCOS patients with infertility have strong high androgen levels and insulin resistance,and obesity factors are associated with endocrine abnormalities.
Medical abortion is a common method to terminate early pregnancy,but in some cases it may lead to abnormal vaginal bleeding.Abnormal vaginal bleeding after drug abortion may be caused by residues in the uterine cavity,poor uterine contraction,uterine infection and other reasons,and will be accompanied by abdominal pain,fever and other symptoms.Abnormal vaginal bleeding can cause physical and psychological discomfort for women.Therefore,it is extremely important to understand the causes,treatment methods and nursing measures of abnormal vaginal bleeding after drug abortion.This paper mainly studies the causes of abnormal vaginal bleeding after drug abortion,abnormal bleeding symptoms and signs,and the corresponding treatment and nursing methods.
[Abstrac]Objective To observe the clinical significance of providing dexamethasone treatment for patients with endometrial polyps while also cooperating with hysteroscopic endometrial polyp resection surgery.Methods 74 patients with endometrial polyps were selected and divided into an experimental group and a control group,with 37 patients in each group,according to the computerized numbering method.The former group of patients underwent hysteroscopic endometrial polyp resection combined with dexamethasone treatment,while the latter group of patients underwent hysteroscopic endometrial polyp resection.Different comparisons were made between the two groups of patients.Results The comparison between the experimental group and the control group showed that the difference in surgical time was not statistically significant(P＞0.05),and the difference in bleeding volume was not statistically significant(P＞0.05);Menstrual volume reminder:Intragroup comparison:lower after 3 months of treatment,and also lower after 6 months.Intergroup comparison showed fewer differences in the experimental group,with statistical significance(P＜0.05).The hemoglobin level indicates that the experimental group is higher(P＜0.05).The comparison of endometrial thickness showed that the experimental group was thinner(P＜0.05).The recurrence rate suggests that the experimental group has a lower recurrence rate,and the difference is statistically significant(P＜0.05).Conclusion For patients with endometrial polyps,the use of dexamethasone combined with hysteroscopic endometrial polypectomy can reduce menstrual flow,improve endometrial thickness,increase hemoglobin levels,and control disease recurrence rates.This method is worthy of clinical promotion.
