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    International journal of biopharmaceutical sciences

    International journal of biopharmaceutical sciences

    Journal

    年发文量

    研究主题

    论文(10)

    排序
    1Alaska's Flora As a Treatment for Cancer.
    Vasiliki Papakotsi, Ashley M Murphy, Madeline L Vagts, Emma J Arsenault,Colin M McGill,Brian M Barth

    Cancer is an extraordinarily complex illness, with many tumors ultimately developing resistance to the currently available therapeutics. This highlights a need for the discovery of new anticancer medicines. Natural products have been utilized for centuries by the indigenous people of Alaska for both spiritual and medicinal purposes and have traditionally been administered as medicine for a wide range of ailments from the common cold to cancer. These plants, including Devil's club, Labrador tea, Western skunk cabbage, and various species of wild berries such as blueberries, lingonberries, salmonberries, and high-bush cranberries, contain a wide variety of natural compounds with therapeutic potential. Various anthocyanins and polyphenols, including quercetin, as well as the pentacyclic triterpenoid ursolic acid, have been identified in these medicinal plants and have demonstrated antioxidant, anti-inflammatory, and anticancer activity. These ethnobotanicals and the unique compounds found within may be integral to the development of novel therapeutics for the treatment of cancer and other conditions.

    2024
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    2The Role of the Microbiome in Cancer and the Development of Cancer Therapeutics.
    Kaitlyn C Belknap,Andrea L Cote,Colin M McGill,Cheryl P Andam,Brian M Barth

    Cancer is caused by a compilation of hereditary and environmental factors. In the past decade, next-generation sequencing has revealed the extent to which the microbiome influences the maintenance of homeostasis and therefore the prevention of diseases such as cancer. Current research efforts explore the interaction between cancer and the microbiome, and the results are anticipated to transform how clinicians approach cancer treatment. There is a plausible transition from the use of human genetic biomarkers to microbiomic biomarkers for genomic diagnostics. Considering the expanding knowledge of the ways in which the microbiome can affect the development of cancer, clinicians treating cancer patients should be considerate of how the microbiome can influence the host-drug or microbiome-cancer interactions. Recognition of the importance of the microbiome within the field of oncology is pertinent to understanding and furthering cancer development and treatment.

    2020
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    3The Non-Biologic-Complex-Drug Concept
    Jacques Rottembourg
    2018
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    4Neutron Spin Echo Spectroscopy and Spin Noise Spectroscopy Comparative Study Onmalignant and Benign Human Cancer Cells and Tissues with the Passage of Time Undersynchrotron Radiation
    Alireza Heidar

    Image Article In the current study, we have experimentally and comparatively investigated and compared malignant human cancer cells and tissues before and after irradiating of synchrotron radiation using Neutron Spin Echo Spectroscopy and Spin Noise Spectroscopy. It is clear that malignant human cancer cells and tissues have gradually transformed to benign human cancer cells and tissues under synchrotron radiation with the passage of time (Figures 1 and 2) [1-106]. It can be concluded that malignant human cancer cells and tissues have gradually transformed to benign human cancer cells and tissues under synchrotron radiation with the passage of time (Figures 1 and 2) [1-106].

    2018引用:36
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    5Analytical Approach for Biosimilar Development: Special Focus on Monoclonal Antibody Biosimilars
    Jun Yuan, Wayne Wenyan Xue,H Fai Poon
    2018引用:4
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    立即登录,查看全部 10 篇论文

    高被引作者

    作者引用发文
    Paul Toran393
    Brian M. Barth395
    David Claxton312
    Fisher Lindsey N312
    McGill Colin M314
    Sally J Gustafson312
    Kriya L. Dunlap312
    Sriram Saravanan Shanmugavelandy251
    Mark Kester251
    Mary Ann Lila251

    高产作者

    作者引用发文
    Brian M. Barth395
    McGill Colin M314
    Paul Toran393
    Sally J Gustafson312
    Kriya L. Dunlap312
    David Claxton312
    Fisher Lindsey N312
    Andrea Cote01
    Mary Ann Lila251
    Sriram Saravanan Shanmugavelandy251

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