Honey has several nutritional and therapeutic uses due to the presence of different bioactive compounds.These substances are derived from floral nectar. Therefore, it becomes essential to identify the distinct chemical profiles of honey samples. The aim of this research was to provide an accurate, straightforward, and sensitive HPTLC approach for different types of honey verification. Eight mono floral honeys (mustard, eucalyptus, litchi, orange, tea, Indian plum, black plum and pineapple) were collected from different origin of West Bengal (eastern India) and examined. Standard procedures were followed to check the quality of each honey.The flora was identified by microscopically examining the pollen found in honeys. High-performance thin layer chromatography (HPTLC) was used to analyze lipophilic fractions of each honey. Chromatographic results identified distinct patterns of bands with specific Rf values for each type of mono floral honey. HPTLC is a simple and effective method for routine analysis and verification. It can serve as authentication for different types of honey.
Fine particle granulation using a spray dryer was performed to prepare with a high drug content, a spherical shape, and a smooth surface. Since the target particle size was less than 200 μm, a rotary disk atomizer was adopted and a slurry was chosen as the spray liquid. When 5-aminosalicylic acid used as a model drug, hydroxypropyl cellulose, and sodium chloride were added in the slurry and was spray dried, the desired size of particles were obtained. Then, the obtained particles were coated with an enteric polymer, no dissolution of the drug in the 1st solution was observed, indicating no disruption occurred during coating.
A basic dissolution study of single granule in a controlled-release capsule formulations was conducted. Controlled-release granules were prepared using porous Ethylcellulose membranes, and single granule dissolution profiles was compared with those of the Japanese pharmacopoeia (JP) paddle method. Dissolution profile from one granule was found to be dependent on the solubility of the drug.
among groups of people who have more than one of these risk factors (e.g., sedentary smokers).While choosing preventive herbal medicines, patients are guided by their own preferences, experience, pharmacists' advice, advertising, etc.In recent years, there has been a growing interest in doctors, pharmacists and patients to a number of original areas of medicine, in particular homeopathy and homeopathic pharmacy.We chose dry clover and calendula extract as the active ingredient.
This minireview summarized a part of the recent work of Professor Mauro Ferrari on the application of mesoporous silicon microparticles to celebrate the occasion of the establishment of a new company, BrYet Pharma. This article is focusing on the principle and application of injectable nanoparticle generators (iNPG) for drug delivery systems. Three main examples are described; deliveries of anti-cancer agents and peptide cancer vaccines using iNPG, and oral formulation of iNPG for inflamed intestinal mucosa. The iNPG drug delivery system provides protection, the versatility of loading, and the selective delivery of therapeutics, which enables prolonged efficacy, the simultaneous delivery of a combination of therapeutics, and the reduction of toxicity. The advantages of the iNPG drug delivery system are discussed with examples in this minireview.
