Background:This study aimed to investigate the effect of different irrigation solutions on the surface roughness of NeoPutty MTA and Biodentine materials used as perforation repair materials. Methods:Thirty-two Teflon blocks were divided into M (NeoPutty MTA) and B (Biodentine) groups, which were further divided into maleic acid (n=8) and ethylenediaminetetraacetic acid (EDTA) (n=8) groups. The surface roughness of all the samples was determined by scanning with an atomic force microscopy (AFM) device before and after soaking in 7% maleic acid and 17% EDTA solutions. For data analysis, the Mann-Whitney U test was used to compare two independent groups, and the Wilcoxon signed rank test was used for dependent groups. Results:According to the findings of the study, no significant difference was found between the initial roughness of NeoPutty MTA and Biodentine materials. However, EDTA solution produced statistically significant surface roughness in Biodentine material, while maleic acid solution produced statistically significant surface roughness in NeoPutty MTA material. Conclusion:Further studies are necessary to investigate the effects of physicochemical changes induced by irrigation solutions in repair materials on bacterial adhesion and restorative adhesive procedures.
Background:The accurate fit between the dental implant and the prosthetic abutment is crucial for the stability of the entire prosthetic-implant system, providing a better distribution of the occlusal load to the surrounding bone. To improve stress distribution between the implant and bone, various types of internal connection implants have been introduced. However, few studies are available on the biomechanical behavior of these connections. This study investigated the stress distribution in screwed implant-supported prosthesis with different implant‒abutment connections using a photoelastic analysis. Methods:Eight photoelastic models were fabricated in PL-2 resin and divided according to the different types of internal connections: Morse taper (MT), internal Morse hexagon (IMH), Morse taper hexagon (MTH), and frictional Morse taper (FMT) implants (3.75×11.5 mm), and the number of crowns (single and 3-unit pieces). Models were positioned in a circular polariscope, and 100-N axial and oblique (45º) loads were applied to the occlusal surface of the crowns using a universal testing machine. The stresses were photographically recorded and qualitatively analyzed using Adobe Photoshop software. Results:Under axial loading, the number and distribution of high-intensity fringes did not differ among groups for both crown types (single and splinted 3-element). Low stress values were noted at the implant apex. The oblique loading increased the number of fringes for all groups. In conclusion, the internal connection tested in this study did not affect the number and distribution of stress. Conclusion:The different types of internal connections provided better stability for the implant‒prosthesis set, which improved stress distribution when the prosthetic pillar was loaded, with the Morse cone friction system showing less stress. Oblique loading resulted in a higher stress concentration than axial loading.
Background:Oral cancer is the eighth leading cause of cancer-related mortality worldwide, particularly prevalent in regions with high tobacco and betel nut consumption. The associated high mortality and morbidity rates could be reduced through early detection, prompting researchers to focus on identifying early markers of carcinogenesis. Methods:This systematic review evaluated the effectiveness of oxidative stress markers as diagnostic tools. An electronic search was conducted in PubMed and Google Scholar to identify case‒control studies published between January 2000 and June 2024 that explored the use of oxidative stress markers as diagnostic biomarkers. A manual search was also performed in relevant journals, including oral oncology and oral diseases. Initially, 38 studies were screened, and after applying the inclusion criteria, only nine studies were included. The Newcastle-Ottawa Scale (NOS) tool was used to assess the risk of bias. Results:Eight studies were conducted in India, while one was from Saudi Arabia. These studies analyzed oxidative stress markers in oral squamous cell carcinoma (OSCC), oral submucous fibrosis (OSMF), and leukoplakia. Control groups were matched based on age and sex, with only two studies also considering socioeconomic status. A significant difference (P<0.05) in oxidative stress marker levels was observed between cases and controls, particularly in patients with OSCC and OSMF. Conclusion:Oxidative stress markers show promise as diagnostic and prognostic indicators. Standardized methodologies and therapeutic approaches targeting oxidative stress could enhance early detection and treatment, especially in resource-limited settings. However, the findings must be interpreted with caution due to methodological limitations, geographic bias, and the lack of inclusion of grey literature.
Background:The oral health needs of older adults must be prioritized due to the shifting demographics of the population and rising life expectancy. This study investigated the prevalence of oral mucosal lesions (OMLs) among geriatric dental patients in a sample of the Egyptian population and explored the association with age, gender, smoking habit, as well as the impact on the quality of life. Methods:This cross-sectional study screened 300 geriatric dental patients aged 65 years or older, from several dental hospitals and mobile clinics in various regions in Egypt. Demographic data and information regarding denture use, systemic diseases, and smoking habits were recorded. A clinical examination was conducted, and the quality of life was assessed using the Oral Health Impact Profile-5 (OHIP-5) score. Results:OMLs were found in 59.3% of the cases studied. The most prevalent OML in the studied population was coated tongue, and the least frequent was oral cancer. The buccal mucosa was the most frequently affected location. OMLs had a profound impact on the quality of life. Male gender, heavy smoking, the presence of medical conditions, and denture use were significant predictors of the presence of OMLs. Conclusion:In the present study, the prevalence of oral lesions in geriatric patients was 59.3%. The most prevalent OML in the studied population was coated tongue, and the least frequent was oral cancer. OMLs had a profound impact on the quality of life. The prevalence of OMLs was found to be strongly linked to systemic diseases, heavy smoking, and male gender.
Background:This trial aimed to compare osseodensification with traditional implant site preparation in terms of clinical outcomes, radiographic findings, interleukin-6 (IL-6), and vascular endothelial growth factor (VEGF) levels in the peri-implant sulcus. Methods:Sixteen patients were randomly assigned to two groups. In group 1, eleven sites received a small-diameter implant according to the conventional method; in group 2, eleven sites received an implant after osseodensification. The modified plaque index, modified bleeding (sulcus) index, and peri-implant probing depth were recorded for all patients on the day of implant placement (baseline) as well as at 3 and 6 months. The preoperative and postoperative alveolar ridge widths were measured, and the marginal bone loss (MBL) around the implant was assessed. Gingival crevicular samples were assayed using ELISA. Results:For the MPI, mSBI, and PPD, no statistically significant differences were reported across the groups at baseline and 3 and 6 months. Group 2 showed a lower marginal bone level and higher bone density, lower VEGF, and lower IL-6 levels than group 1. Conclusion:Osseodensification was shown to preserve bone and augment the ridge width, unlike conventional osteotomy with a small-diameter implant. The association of VEGF and IL-6 may be used as a marker for bone resorption and revascularization around dental implants.
