The aim of this study was to evaluate the oncological justification for multivisceral pancreaticoduodenectomy with resection of the venous confluence (superior mesenteric and/or portal vein) in patients with pancreatic ductal adenocarcinoma (PDAC) of the pancreatic head. In this retrospective observational cohort study, we enrolled 107 consecutive patients with PDAC of the pancreatic head who underwent pancreaticoduodenectomy with SMV/PV resection at two specialized oncological centers between January 2011 and April 2024. We estimated overall survival (OS) and recurrence-free survival (RFS) by the Kaplan–Meier method, assessed prognostic factors by Cox proportional-hazards regression, and built multivariate models by forced entry (enter) of the variables that reached p < 0.10 in univariate analysis, with the number of predictors limited by the events-per-variable rule. Fifteen patients underwent multivisceral surgery with pancreaticoduodenectomy (MVS + PD; concurrent resection of one or more adjacent organs in addition to venous resection) and 92 underwent standard pancreaticoduodenectomy (PD) with venous resection alone. Severe postoperative complications (Clavien–Dindo grade ≥3a) occurred in 26.2
Intraductal papillary mucinous neoplasms (IPMNs) are commonly detected incidentally. International guidelines recommend surveillance of branch-duct IPMN (BD-IPMN) in the absence of surgical indications. However, the incidence of IPMN-related cancer in younger populations remains unclear. This study aimed to evaluate the risk of IPMN-related pancreatic cancer (PC) in patients under 65 years of age. The study population consisted of two groups. The first included all patients enrolled in a BD-IPMN surveillance program. The second comprised all patients diagnosed with PC in Pirkanmaa region, Finland, between 2014 and 2023. Demographic data, pancreatic imaging findings, and histological diagnoses were obtained from patient records. Of the 574 patients in the BD-IPMN surveillance program, 198 were younger than 65 years. Four patients (2.0
To evaluate the safety and efficacy of enhanced recovery after surgery (ERAS) in patients undergoing ureteroscopic lithotripsy (URL). PubMed, Embase, the Cochrane Library, Web of Science, CNKI, VIP, Wanfang Data, and SinoMed were searched through 20 November 2025. The primary analysis was restricted to trials reporting an identifiable random-sequence generation method; reports with unclear sequence generation were added in a post hoc sensitivity analysis. Meta-analyses were performed in Review Manager 5.4.1. Twenty-five trials (2,372 participants) were included in the primary analysis, and 15 additional reports were added only in the 40-trial sensitivity analysis. ERAS shortened postoperative hospital stay (12 trials; MD − 1.59 days, 95
Elastofibroma dorsi (ED) is a benign soft-tissue tumour typically located in the subscapular region. Hounsfield unit (HU) measurements on computed tomography (CT) may provide quantitative information on lesion attenuation. This study aimed to compare patient-level HU values of ED with those of adjacent skeletal muscle. This retrospective, single-centre study included 11 surgically treated patients with histopathologically confirmed ED. Preoperative CT examinations suitable for HU analysis were available for nine patients. For patients with bilateral measurements, right- and left-sided values were averaged to obtain one ED and one adjacent serratus anterior muscle value per patient. Paired differences were assessed for normality and compared using a paired-samples t test. Ten patients (90.9
The optimal minimally invasive strategy for selected patients with moderate-volume deep intracerebral hemorrhage (ICH) remains uncertain. We compared staged stereotactic catheter drainage with urokinase thrombolysis and neuroendoscopic evacuation in patients with 20–40 mL hypertensive basal ganglia ICH. We retrospectively analyzed 48 patients treated from January 2022 to December 2024: 21 underwent stereotactic catheter drainage followed by once-daily urokinase and 27 underwent neuronavigation-assisted neuroendoscopic evacuation. None of the patients had intraventricular extension, and all underwent a first postoperative CT within 24 h of surgery. In the catheter group, this scan was obtained before the first urokinase administration. The main comparative clinical outcome was the 3-month modified Rankin Scale (mRS). A proportional-odds model adjusted for age, admission Glasgow Coma Scale score, and baseline hematoma volume. Catheter-lysis had shorter operative time (44 [39–48] vs. 117 [106–133] min), less blood loss (12 [10–14] vs. 150 [100–200] mL), and lower hospitalization cost (CNY 31,005 [26,048–38,909] vs. 59,655 [50,038–73,495]; all P < 0.001). Neuroendoscopy achieved greater early postoperative hematoma reduction on the first postoperative CT: residual hematoma volume was 4.0 [3.0–10.7] versus 13.5 [12.0–21.3] mL, and hematoma clearance was 81.3
