Aim: To describe self-disclosure, social support, and fear of cancer recurrence (FCR) in breast cancer patients, explore their correlations, analyze factors influencing FCR, and examine the mediating role of social support between self-disclosure and FCR. Design: Cross-sectional survey design. Methods: A cross-sectional study of 350 breast cancer patients recruited from a tertiary tumor hospital in Guangzhou. Data were collected using general information questionnaire, Fear of Progression Questionnaire-Short Form, Distress Disclosure Index, and Social Support Rating Scale. Results: The total FCR score was 33.43 ± 8.00, with 46.3% of patients scoring ≥ 34. Self-disclosure score was 38.75 ± 9.18, and social support score was 70.57 ± 14.04. Univariate analysis showed that age, economic burden, family relationship, and sleep status significantly influenced FCR (P < 0.05). Multivariate analysis showed that four variables—patient age, sleep status, self-disclosure, and social support—had a significant impact in the multivariate analysis of the physical health dimension of FCR (P < 0.05); patient age, economic burden, self-disclosure, and social support had a significant impact in the multivariate analysis of the social and family dimension of FCR (P < 0.05). Self-disclosure and social support were negatively correlated with FCR (r = -0.311 to -0.400, P < 0.01). Structural equation modeling revealed that social support partially mediated the relationship between self-disclosure and FCR, with a mediating effect of 30.4%. Patient or Public Contribution: Breast cancer patients who received treatment at a tertiary-level Class A oncology hospital in Guangzhou between February and July 2023.
Objectives: Robotic technologies increasingly shape how cancer care is delivered and experienced, but the literature remains focused on platforms and conventional clinical outcomes. This systematic evidence map examined publication growth and thematic structure from 2016 to 2025 and assessed the visibility of patient-reported, psychosocial, social, ethical, and implementation concerns. Methods: Web of Science and Scopus articles and reviews were harmonized, deduplicated, and screened using a rule-assisted workflow. The primary corpus comprised 12,587 eligible records; 12,274 records with abstracts underwent non-negative matrix factorization. An expanded-search diagnostic sample included 620 records, of which 87 were marked for inclusion by both assessors and added to a 12,674-record audit inventory. Unmatched records were not screened exhaustively, and all estimates derive from the primary corpus. Results: Annual output rose from 746 records in 2016 to 1,944 in 2025, and robot-assisted oncologic surgery accounted for 81.6% of records. The ten topics clustered around cancer sites, procedures, evidence synthesis, and conventional outcomes; none focused primarily on psychological or social care. Patient-centered indicators were visible in 2,462 records (19.6%). The expanded audit did not alter the primary-corpus estimates. Conclusion: Despite rapid publication growth, patient-centered concerns did not become more visible in the metadata over time. The map captures the presence of psychosocial constructs in indexed metadata, not their measurement with validated instruments or their effects. Future studies should pair clinical outcomes with psychological adjustment, decision quality, social participation, caregiver effects, accessibility, and ethical safeguards.
The early detection of hyperglycemic states, while clinically beneficial, often introduces significant psychological burden and health-related anxiety due to the uncertainty of a pre-diagnostic phase. This study aims to evaluate the diagnostic utility of combining Fasting Plasma Glucose (FPG) and Oral Glucose Tolerance Test (OGTT) in a community setting, and to discuss how this screening strategy, when integrated into a structured community management program, can serve as a psychosocial intervention to alleviate health-related anxiety and uncertainty in a high-risk population. In an experimental study, 1,586 high-risk individuals for type 2 diabetes in Jiading Town, Shanghai, were screened. Those with FFG levels between 5.6 mmol/L and 8.0 mmol/L (n = 321) underwent further FVBG and 2-hour OGTT testing. The diagnostic performance of these tests was evaluated using ROC curves. The findings were interpreted within the framework of community-based psychosocial support and chronic disease management to reduce patient distress. The prevalence of hyperglycemia was 13.62%, with prediabetes accounting for over half of these cases (56.02%). ROC analysis demonstrated that FVBG (AUC = 0.850) and OGTT2h (AUC = 0.981) were highly effective diagnostic tools, whereas FFG alone (AUC = 0.666) showed limited value. The community management system, by providing clear diagnostic pathways, helped mitigate the distress associated with ambiguous health statuses, particularly in older adults ( >= 55 years) and males, who exhibited higher rates of diabetes. The combined use of FPG and OGTT in community-based screening is not only a clinically effective diagnostic strategy but also a vital component of a broader psychosocial intervention model. By providing clear and definitive diagnostic information, it reduces health-related uncertainty and anxiety, empowering patients to engage in proactive health management. This model highlights the importance of integrating mental health considerations into primary care chronic disease management.
Background: The relationship between 31 types of fat/oil used in cooking and various forms of abortion (habitual aborter, medical abortion, pregnancy with abortive outcome, spontaneous abortion, unspecified abortion, and other abortion) in women is unclear. This study aims to investigate this relationship using bidirectional Mendelian randomization (MR) analysis. Methods: Significant SNPs associated with types of fat/oil used in cooking (P < 5e-8) were extracted as instrumental variables (IVs) after clumping. Five MR methods, including inverse variance weighted (IVW), were employed to assess the relationship, with IVW, MR-Egger, and leave-one-out analyses used for sensitivity analysis. Associations with FDR-corrected P < 0.05 were considered statistically significant. For statistically significant associations, reverse MR was performed to assess potential reverse causality, extracting SNPs associated with abortion outcomes (P < 5e-6) as IVs. Results: After FDR correction, low-fat olive spread showed evidence of a potential association with spontaneous abortion (OR [95% CI] = 771.35 [16.50, 36068.62], P = 7.00E-04). Additionally, cholesterol-lowering olive spread showed evidence of a potential association with pregnancy with abortive outcome (OR [95% CI] = 4.01 [1.68, 9.58], P = 1.70E-03). Sensitivity analyses did not detect evidence of pleiotropy or heterogeneity. Reverse MR analyses did not support reverse causality. Conclusion: This bidirectional MR analysis suggests that selected cooking fat/oil choices, particularly low-fat olive spread and cholesterol-lowering olive spread, may be associated with spontaneous abortion and pregnancy with abortive outcome, respectively. Given the exploratory design and wide confidence intervals, especially for low-fat olive spread, these findings should be interpreted cautiously and considered hypothesis-generating until validated in larger independent studies.
Background: Urinary incontinence (UI) is a common complication after radical prostatectomy and can affect daily functioning, social participation, emotional wellbeing, and quality of life. Pelvic floor muscle exercise (PFME) is a first-line conservative intervention, but the added value of combining PFME with other rehabilitation modalities remains uncertain. This review evaluated continence outcomes and explored reported quality-of-life and psychosocial outcomes. Methods: CNKI, WanFang, the Chinese Biomedical Literature Database, CENTRAL, Embase, Web of Science, and PubMed were searched for randomized controlled trials published from January 2000 to June 2025. Eligible studies compared a PFME-based combined intervention with PFME alone after radical prostatectomy. Continuous outcomes were synthesized using mean differences (MDs) or standardized mean differences (SMDs), and continence-recovery events were synthesized using risk ratios (RRs) based on the original studies' definitions. Leave-one-out analyses assessed robustness. Certainty was evaluated using GRADE; heterogeneous quality-of-life and psychosocial outcomes were summarized narratively. Results: Eleven studies contributed 839 participants to the relevant pairwise comparisons. Pooled estimates favored PFME plus acupuncture for 1-hour pad-test leakage (SMD = -1.65, 95% CI-2.00 to-1.30), PFME plus electrical stimulation for International Consultation on Incontinence Questionnaire-Urinary Incontinence-Short Form (ICIQ-UI SF) scores (SMD = -0.85, 95% CI-1.20 to-0.50), PFME plus biofeedback for continence recovery (RR = 1.49, 95% CI 1.24 to 1.79), and PFME plus vibratory therapy for 24-hour pad-test leakage (MD = -17.10 g, 95% CI-20.39 to-13.81). Certainty was low for the continuous outcomes and very low for continence recovery. Leave-one-out findings were stable except for vibratory therapy, for which removal of the dominant study rendered the estimate non-significant. Two studies reported heterogeneous quality-of-life or psychosocial outcomes; no dedicated psychological outcome could be pooled. Conclusions: Low certainty evidence suggests that selected adjuncts may improve specific continence outcomes when added to PFME. Because each adjunct was evaluated using a different outcome and no head-to-head evidence was available, the modalities cannot be ranked. The psychological effects of improved continence also remain uncertain. Larger multicenter trials should use standardized continence definitions, common follow-up points, and validated psychological and quality-of-life measures.
