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    Seminars in Arthritis and Rheumatism

    Seminars in Arthritis and Rheumatism

    JournalISSN 0049-0172eISSN 1532-866X中科院 医学 2区

    年发文量

    研究主题

    论文(4362)

    排序
    1Biomarker Trajectories and Risk of Relapse in Giant Cell Arteritis: a Multicenter Study
    Samuel PICHON,Amélie LEURS, Léa MORTAIN,Hélène BEHAL, Naoual DALHI,Mathieu JOUVRAY,Vincent KOETHER,Emmanuel LEDOULT,Aurelien CHEPY,Eric HACHULLA,Vincent SOBANSKI,David LAUNAY,
    2026
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    2Anti-phosphatidylserine/prothrombin Antibodies in Antiphospholipid Syndrome: Clinical Associations and Methodological Heterogeneity—a Scoping Review
    H. Parikh, G. Gobbo, M. Colesanti, J. Dass,E. Esteve-Valverde,J. Alijotas-Reig, P. Simioni, A. Hoxha
    2026
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    3The Ecology of Autoimmunity: Influence of Pollution on the Development of Polygenic Autoimmune Diseases
    Ivana Stojkic, Julie A. Dougherty,Gaofu Zhang,Jon Klein,Stacy P. Ardoin,Brad Rovin,Howard Trachtman,William E. Smoyer
    2026
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    4Gender Equity in the Global Rheumatology Workforce: Results of the Coalition for Health and Gender Equity (CHANGE) Survey
    Latika Gupta,Manali Sarkar,Pavel Ovseiko,Laure Gossec, Taanya Talreja,Jessica Day,Lisa Traboco,Anne Marie Russell,Syed Atiqul Haq,Catherine L. Hill,Dzifa Dey,Neelam Hassan,

    Background/Purpose Gender equity remains an elusive goal across many specialist medical fields. The Coalition for Health and Gender Equity (CHANGE) conducted a comprehensive global survey assessing gender equity within the international rheumatology workforce. Methods A cross-sectional online survey of rheumatologists and allied health professionals was conducted between January 2023 and May 2024. The 38-item survey covered demographics, gender discrimination, sexual harassment, work-family interface, and career advancement. It was translated into eight languages and disseminated through professional organisations, mailing lists and social media channels in 105 countries. Analyses included descriptive statistics and comparative tests, with gender differences evaluated after adjustment for years of work experience. Subgroup analyses included country Human Development Index (HDI), professional roles, and caregiving responsibilities, with statistical significance set at p<0.05. Results Among 1,945 respondents (66.4% female), pronounced gender-based disparities were observed. Male professionals demonstrated higher rates of full-time employment, leadership positions, and clinical experience. Female rheumatology professionals more frequently encountered career barriers, including tasks below their expertise, hostility from colleagues, lacking leadership training opportunities, lower remuneration, and difficulties securing research funding. Women reported greater domestic responsibilities (47.5% vs 36.2%, p<0.001) and higher work-family conflict, with nearly four times the odds of experiencing sexual harassment and double the odds of experiencing bullying. Perceived experiences were more pronounced among respondents from high-HDI countries and those with caregiving responsibilities, but did not differ by professional role. Conclusion This global survey provides compelling evidence of gender disparities in rheumatology, necessitating coordinated, evidence-based interventions to address structural barriers and promote inclusive cultures.

    2026
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    5Diffuse Idiopathic Skeletal Hyperostosis is Associated with Reduced Lung Function Independent of Structural Lung Abnormalities
    Netanja I. Harlianto,Sytse F. Oudkerk,Pim A. de Jong,Esther Pompe,Wouter Foppen,Jorrit-Jan Verlaan,Rozemarijn Vliegenthart,Harry J.M Groen,Firdaus A.A. Mohamed Hoesein

    Introduction Diffuse idiopathic skeletal hyperostosis (DISH) has been associated with lower lung volumes and function, but it is unknown whether this is due to structural lung disease. This study aimed to investigate DISH and reduced lung function and volume in relation to structural lung disease in individuals with long-term smoking history. Methods Participants were included from the NELSON lung cancer screening trial. Structural lung abnormalities were automatically quantified (emphysema, airway wall thickness, and air trapping), or visually assessed (interstitial lung abnormalities, bronchiectasis, centrolobular emphysema) by two chest radiologists. Multivariate linear regression analyses were performed with adjustment for participant factors and structural lung disease. Results Among 3514 subjects (100% male, mean age 60.4 years), DISH was present in 241 (6.7%). Individuals with DISH had lower prevalence of Respiratory Bronchiolitis Interstitial Lung Disease (5%vs. 10.4%, p = 0.04) and of centrilobular emphysema (3.3%vs. 7.6%, p = 0.009), but greater airway wall thickness (2.6 vs. 2.4 mm, p < 0.001). In multivariate linear regression analyses, DISH subjects had a 4.4% lower FEV1 (95%CI: -7.1% to -1.7%), 150 ml lower FEV1 (95%CI: -160, -140 ml), 4.0% lower predicted FVC (95%CI: -6.2%, -1.7%), 170 ml lower FVC (95%CI: -280, -70 ml) and 210 ml lower CT measured lung volume (95%CI: -40, -1 ml), compared to subjects without DISH. Conclusion In long-term smokers, DISH was associated with lower lung function and volumes, not explained by structural lung abnormalities on CT. These findings suggest that DISH may be an extrinsic factor contributing to reduced lung function as a result of thoracic cage stiffening.

    2026
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    高被引作者

    作者引用发文
    Marc C. Hochberg324329
    Jaime Branco279213
    Jean-Yves Reginster276916
    Jean-Pierre Pelletier246716
    Cyrus Cooper246017
    Miguel A. Gonzalez-Gay224832
    BRUYÈRE Olivier218810
    Yehuda Shoenfeld216922
    Alfonse T. Masi21228
    Johanne Martel-Pelletier208914

    高产作者

    作者引用发文
    Christensen Robin96657
    Beverley Shea39754
    Peter Tugwell73946
    Nicola Dalbeth78744
    Jeffrey A Sparks77940
    Dafna Gladman95237
    Santos Castañeda119737
    Dorcas E. Beaton32234
    Cynthia S. Crowson69233
    Miguel A. Gonzalez-Gay224832

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