Background Bone grafting is essential for alveolar clefts. Sticky bone combined with concentrated growth factor (CGF) may enhance stability and healing compared to conventional methods, reducing resorption and donor site morbidity. Purpose To evaluate using sticky bone grafting combined with CGF membrane for repair of unilateral alveolar cleft. Patients and methods Ten patients with unilateral alveolar clefts were clinically evaluated for oronasal fistulas and nasal regurgitation. Cone-beam computed tomography (CBCT) scans assessed cleft dimensions and defect volume. Surgery involved raising mucoperiosteal flaps, suturing nasal lining, applying CGF membrane, grafting with sticky bone, then covering with another CGF membrane before flap closure. Patients were followed for 9 months to assess clinical outcomes (inflammation, nasal regurgitation, and fistula recurrence) and radiographic outcomes (graft volume and bone mineral density). Results Eight patients showed uneventful healing. Graft volume decreased from 1399.25 ± 418.63 mm 3 immediate postoperatively to 593.96 ± 242.63 mm 3 at 3 months, then increased to 825.93 ± 242.16 mm 3 at 9 months (mean graft take: 60.51 ± 11.68%). Bone mineral density at the graft site increased over time, reflecting ongoing mineralization, and remained higher than that in adjacent areas. Conclusions Sticky bone with CGF membrane enhances graft stability and integration in alveolar cleft repair. CBCT proved vital for volumetric and density assessment, supporting its role in long-term monitoring and treatment planning. Clinical relevance Sticky bone with CGF membrane enhances stability and healing in unilateral alveolar cleft repair, with CBCT enabling reliable postoperative assessment.
Background Antihistamines that are frequently used in treating allergic reactions are known with adverse effects. They are used to treat allergic rhinitis and urticaria. Vitamin-C (Vit-C) is a powerful antioxidant, able to reduce free radicals production and minimizes oxidative stimuli generated by chemical and environmental factors. Aim To identify the effects of Vit-C on the desloratadine degenerative changes on the acini of submandibular glands in albino rats histologically and ultrastructurally. Materials and methods Forty-five male albino rats were distributed as; control group (Gp I): received saline orally. Desloratadine-treated group (Gp II): received desloratadine (0.245 mg/kg) orally for 21 days. Desloratadine/Vit-C-treated group (Gp III): rats were treated as Gp II and with vitamin-C (500 mg/kg) orally for 21 days. Glands were examined using light and transmission electron microscopes. Area percentage of acini was statistically analyzed. Results Gp II acini were widely separated with cytoplasmic vacuolations. Nuclei showed irregular outline, some were pyknotic and shrunken. Rough endoplasmic reticulum showed dilatation and mitochondria were swollen. In Gp III, spaces between acini were less and showed minimal vacuolations. Some rough endoplasmic reticulum were well-developed, others were fragmented and mitochondria were almost normal. Statistical analysis revealed area percentage of acini was significantly decreased in Gp II when compared Gp I and Gp III. Gp III showed a significantly decreased mean value as contrasted to Gp I and significant increase when contrasted to Gp II. Conclusions Desloratadine showed adverse effects on submandibular glands’ acini under light and transmission electron microscope. Vit-C enhanced these changes.
Abstract Aim: The aim of this in-vitro study was to evaluate the passive fit of screw-retained fixed/detachable digital denture framework fabricated from poly-ether-ether-ketone (PEEK) material using conventional and digital methods and comparing it with a denture framework fabricated from cobalt-chrome (Co-Cr) alloy. Material and methods: One readymade mandibular completely edentulous epoxy resin model covered with silicon resilient was used. Four implant analogs were placed at zero tilt on each cast multiunit abutments (MUA) and scanned with the epoxy resin cast by extra oral scanner and 3D virtual copy model was made. Outputting stereolithography (STL) file was saved and used as reference cast. The epoxy resin model with silicon was duplicated and poured in type IV stone that scanned and saved as STL file. Fourteen frameworks were designed as a duplication of the single ideal model and saved as STL file. Half of the frameworks were fabricated digitally from Co-Cr and the other half from PEEK. Passive fit was assessed for all dentures framework by conventional method and digital method. In conventional assessment of passive fit one screw was tightened on one side and the marginal fit was evaluated on the other sides by measuring the gap between the edge of MUA and the framework. Digital assessment of passive fit was made by using computer-aided design/computer-aided manufacturing software program and superimposition was made with the software demonstrating the amount of deviations between the prostheses and reference cast. Results: The result of this in-vitro study showed a significant difference between the two different material frameworks (PEEK and Co-Cr) regarding the gap between MUA and framework. However, the gap value was less in PEEK than Co-Cr. Conclusions: It was concluded that denture framework fabricated from PEEK has better passive fit compared to denture framework fabricated from Co-Cr using conventional and the digital evaluation.
Abstract Background: Today implants demonstrate high survival rate due to improved biological knowledge and enhanced practical skills. Placement of provisional restoration immediately at the same time of implant help to preserve the gingival tissue height and profile. Purpose: The aim of this clinical study was to evaluate effect of different implant provisionalization on success of final restoration. Materials and methods: The study comparing the two different provisional materials of implant-supported restoration (BIRILLANT CRIOS, reinforced composite in GI and PMMA in GII) using PD, POB, MBL, and PI. Results: Regarding PD in GI is 2.38 ± 0.52, 2.63 ± 0.5 mm and GII is 2.75 ± 0.89, 3.13 ± 0.84 mm, respectively. Regarding MBL in GI IS 0.775 ± 0.39, 0.20–1.50 mm and in GII is 0.350 ± 0.14, 0.10–0.50 mm BOP in GII from +ve to −ve and half of cases of GI, PL in GI from 3.2 to 1 mm and from 2 to 1 mm in GII. Conclusion: Null hypothesis of this study was accepted; the two materials are considered implant provisionalization.
Abstract Objective: The present study aimed to evaluate the precision of dental measurements on stone and digital models derived from CBCT and extraoral desktop scanning. Materials and methods: Twenty-two pairs of pretreatment models (upper and lower) were scanned using a Medit T310 desktop scanner. The same models were also scanned using a Planmeca ProMax 3D Classic CBCT scanner. DICOM files were converted into Standard Tessellation Language format using the scanner’s proprietary software. All Standard Tessellation Language files obtained from both scanning methods were imported into Maestro 3D software for analysis. Measurements from plaster study models were compared with those from digital models. Statistical evaluations included the intraclass correlation coefficient, Bland–Altman analysis, multivariate analysis of variance, and post-hoc Tukey’s test. Results: High intraclass correlation coefficient values were observed for both CBCT and desktop scanners. Bland–Altman plots showed insignificant differences in mean values between methods. Multivariate analysis of variance revealed no statistically significant differences in mesiodistal tooth dimensions or arch-width measurements across the three model types. Conclusion: Digital models derived from desktop and CBCT scanning appear to be accurate and precise for dental measurements and may effectively replace conventional stone models.
