The influence of the various pharmaceutical factors on the release of active substances from matrix tablets based on interpolyelectrolyte complexes of a poly (methacrylic acid) and poly(ethylene glycol) was studied. By varying these factors, it is possible to control the drug release kinetics and create new medicinal forms with preset pharmacological properties. The most important factors are the polymer fraction in the composition and the character of interaction between the active substance and matrix components.
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